Genetically Altered Animal Models
Related to Heart, Lung, Blood, or Sleep
Search the Animal
Models Database
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Welcome to the NHLBI Genetically Altered Animal
Models Web Page. Each entry in the database corresponds to a Medline article,
published in 1995 or later, that describes a genetically altered animal model
of a disease or condition related to the heart, lung, or blood, or a sleep
disorder. Models are included in the database once --- the first time they are reported on in a Medline peer-reviewed article.
(Models developed for other purposes, but used for the first time to
study an NHLBI-related disease or condition, are also included.) Included for
each entry are: an indication of the general area of applicability (i.e.,
heart, lung, blood, and/or sleep), the gene manipulated, the type of
manipulation (i.e., transgenic, knockout, or "other") involved, the disease or
condition under study, and the kind of animal used. Each entry is linked to the
Medline abstract.
You can select any gene or disease/condition you are
interested in from the corresponding menu, or you can use the text search box
to search for a string of characters appearing anywhere in any field. The text
search strategy ensures that you receive all variations of a term.
Click on the arrow (in the Abstract column) of any
animal model retrieved to link to the corresponding Medline abstract. When you
are finished reading the abstract, close the window to return to the NHLBI
Animal Models Web Page.
This web page is updated periodically. If you would
like to suggest for inclusion a model that was developed (or used for the first
time) in 1995 or later to study a disease or condition related to the heart,
lung, or blood, or a sleep disorder, please send the complete citation for the
original article describing the model to the Animal Model Web Page Coordinator,
E-mail: (ss100g@nih.gov).
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