Scientific Area of Research
Includes identifying the genes that cause neurological disorders. Includes collecting family data and applying molecular genetic
methodologies for gene identification. Investigating the molecular mechanisms through which disease genes act. Includes using
animal models and in vitro techniques for studying pathways of gene function. Developing gene-based therapeutics for neurological
disorders. Includes gene therapy and pharmaceuticals targeted to specific gene products. Investigating the genetic basis of
normal neural development and function. Includes genetically-based studies of neuronal patterning, migration, connectivity,
and cognitive/behavioral function. Developing resources for neurogenetic research. Includes tissue and information registries,
atlases of gene expression and function, and mutagenesis and phenotyping methodologies.
Current Funding Announcements
*Note: The
Electronic Submission process for grant applications has begun at NIH. Register with
Grants.gov and
NIH eRA Commons so that you may
start preparing for this transtion
Funding announcement information is updated daily throughout the NINDS website. If individual funding announcements are not
listed below, it means that there are no current solicitations available for this particular Program Area. Please continue
to check this web page for the latest RFA's, PA's, RFP's and Notices related to this Program Area.
Requests for Application (RFA)
(Sorted by Application Receipt Date)
-
Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure “Grand Opportunities” (RC2) [Summary]
Application Receipt Date: May 27, 2009
Letter of Intent Date: April 27, 2009
Announcement Number: RFA-OD-09-004
Funding Contact:
Emmeline Edwards, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Office Of International Activities, Systems and Cognitive Neuroscience, Office of Clinical Research
-
Recovery Act Limited Competition: Academic Research Enhancement Award (R15) [Summary]
Application Receipt Date: September 24, 2009
Announcement Number: RFA-OD-09-007
Funding Contact:
Randall Stewart, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Office Of International Activities, Systems and Cognitive Neuroscience, Administrative Services Branch
Program Announcements (PA)
(Sorted by Application Receipt Date)
-
Research Supplements to Promote Diversity in Health-Related Research [Summary]
Application Receipt Date: May 15, 2009
Announcement Number: PA-08-190
Funding Contact:
Michelle Jones-London, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Systems and Cognitive Neuroscience, Office of Clinical Research
-
Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers [Summary]
Application Receipt Date: May 15, 2009
Announcement Number: PA-08-191
Funding Contact:
Michelle Jones-London, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Systems and Cognitive Neuroscience, Office of Clinical Research
-
Development of In-Vitro Assays to Assess the Potency of Botulinum Neurotoxin Type A (SBIR [R43/R44]) [Summary]
Application Receipt Date: August 5, 2009
Announcement Number: PA-09-179
Funding Contact:
Danilo Tagle, Ph.D.
Program Area:
Neurogenetics
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Development of In-Vitro Assays to Assess the Potency of Botulinum Neurotoxin Type A (STTR [R41/R42]) [Summary]
Application Receipt Date: August 5, 2009
Announcement Number: PA-09-178
Funding Contact:
Danilo Tagle, Ph.D.
Program Area:
Neurogenetics
-
Enhancing Zebrafish Research with Research Tools and Techniques (R01) [Summary]
Application Receipt Date: September 17, 2009
Letter of Intent Date: August 17, 2009
Announcement Number: PAR-08-139
Funding Contact:
Robert Riddle, Ph.D.
Program Area:
Neurogenetics
Notices (NOT)
(Sorted by Release Date)
-
NIH/AHRQ Confirms Plans to Transition the G7, G8, G11, G13, G20, S11, S21 and S22 to Electronic Applications and Announces
Delay in Transition of K, F, T and Complex Grant Programs [Summary]
Release Date: January 19, 2007
Announcement Number: NOT-OD-07-038
Funding Contact: NINDS Funding
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Systems and Cognitive Neuroscience, Office of Clinical Research
-
Policy Revision of the National Institute of Neurological Disorders and Stroke (NINDS) for Competing Program Project (P01)
and Unsolicited Center Grant (P50) Applications [Summary]
Release Date: May 15, 2007
Announcement Number: NOT-NS-07-010
Funding Contact:
Robert Finkelstein, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Systems and Cognitive Neuroscience, Office of Clinical Research
-
Amendment to NOT-NS-07-010: Policy Revision of the National Institute of Neurological Disorders and Stroke (NINDS) for Competing
Program Project (P01/P50) Grant Applications [Summary]
Release Date: February 6, 2008
Announcement Number: NOT-NS-08-010
Funding Contact:
Emmeline Edwards, Ph.D.
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Systems and Cognitive Neuroscience, Office of Training and Career Development, Office of Clinical Research
Administrative and Research Supplements
(Sorted by Release Date)
-
NIH Announces the Availability of Recovery Act Funds for Administrative Supplements [Summary]
Release Date: March 16, 2009
Announcement Number: NOT-OD-09-056
Funding Contact: NINDS Funding
Program Area:
Neural Environment, Neurodegeneration, Neurogenetics, Repair and Plasticity, Office of Translational Research, Office of Training and Career Development, Office of Minority Health and Research, Channels, Synapses and Neural Circuits, Office Of International Activities, Systems and Cognitive Neuroscience, Office of Clinical Research
Also See:
http://www.ninds.nih.gov/recovery/
View Archived Announcements
Additional Information
Mission Statement
The Human Genetics Resource Center
Neurogenetics Group Personnel
Mission Statement
Genetic methodologies are having a rapidly increasingly impact on studies of the normal and diseased nervous system. To date,
more than 200 genes have been identified that cause or contribute to neurological disorders. It is essential that neuroscientists
exploit the power of modern molecular genetics and use the information becoming available from sequencing of the human genome.
The Neurogenetics Cluster will:
- promote efforts to identify neurological disease genes.
Identifying genes that, when mutated, cause neurological disorders will permit improved diagnosis and ultimately treatment
of these disorders. We will coordinate the collection of family data required to identify disease genes, and encourage exploratory
research that utilizes this data for gene discovery.
- promote investigation of the mechanisms by which genetic mutations cause neurological disease.
Once disease genes are identified, the challenge is to determine how mutations in these genes lead to disease. We will encourage
the development of animal models for studying pathways of gene function, investigating how these pathways are disrupted by
genetic alterations, and ultimately for testing therapeutic interventions.
- develop gene-based therapeutics for neurological disorders.
The nervous system presents unique problems for gene therapy and the development of drugs targeted to specific gene products.
Among the most pressing are introducing genes across the blood-brain barrier, targeting gene expression to specific brain
regions, and promoting sustained gene expression. We will coordinate research in these areas, and promote the identification
of molecular targets for pharmacological intervention.
- develop resources for neurogenetic research.
It is critical that recent advances in genetic technology be made widely available to the neuroscientific community. We will
promote the development of gene expression maps of the brain, novel mutagenesis and phenotyping strategies, functional genomic
methodologies, and more powerful techniques for linkage analysis of multigenic diseases.
- promote basic research in neurogenetics.
Increased knowledge of the genetic basis of neural development and function will provide a foundation for progress in all
the areas described above. We will foster research involving the genetic mechanisms that control neural development, including
pattern formation, cell migration, axon guidance, and related processes. We will also promote the investigation of the genetic
underpinnings of behavior and cognition, including sleep, learning, memory, and emotion.
The Human Genetics Resource Center: DNA and Cell Line Repository
The NINDS Human Genetics Resource Center at the Coriell Institute is a growing bank for human cells, DNA samples, clinical data, and information sources, to accelerate
research on genetics of disorders of the nervous system. Its mission is to provide genetics support for scientists investigating
pathogenesis in the central and peripheral nervous networks and information support for patients, families, and advocates
concerned with the living-side of neurological disease and stroke. More...
Quick Links
NINDS Muscular Dystrophy Page
Muscular Dystrophy Coordinating Committee (MDCC)
Workshops and Summaries
Personnel
Address
Neurogenetics
6001 Executive Blvd
Room 2136
Bethesda, MD 20892
Phone: (301) 496-5745
Fax: (301) 402-1501
For courier service only, use Rockville MD, 20852