Tourette syndrome (TS) is a neurological disorder characterized by repetitive, stereotyped, involuntary movements and vocalizations called tics. The first symptoms of TS are almost always noticed in childhood. Some of the more common tics include eye blinking and other vision irregularities, facial grimacing, shoulder shrugging, and head or shoulder jerking. Perhaps the most dramatic and disabling tics are those that result in self-harm such as punching oneself in the face, or vocal tics including coprolalia (uttering swear words) or echolalia (repeating the words or phrases of others). Many with TS experience additional neurobehavioral problems including inattention, hyperactivity and impulsivity, and obsessive-compulsive symptoms such as intrusive thoughts/worries and repetitive behaviors.
Because tic symptoms do not often cause impairment, the majority of people with TS require no medication for tic suppression.
However, effective medications are available for those whose symptoms interfere with functioning. There is no one medication
that is helpful to all people with TS, nor does any medication completely eliminate symptoms. Effective medications are also available to treat some of the associated neurobehavioral disorders that can occur in patients
with TS.
Although TS can be a chronic condition with symptoms lasting a lifetime, most people with the condition experience their worst
symptoms in their early teens, with improvement occurring in the late teens and continuing into adulthood. As a result, some individuals may actually become symptom free or no longer need medication for tic suppression.
The National Institute of Neurological Disorders and Stroke (NINDS) and other institutes of the National Institutes of Health
(NIH) conduct research in laboratories at the NIH and also support additional research through grants to major medical institutions
across the country. Knowledge about TS comes from studies across a number of medical and scientific disciplines, including genetics, neuroimaging,
neuropathology, clinical trials (medication and non-medication), epidemiology, neurophysiology, neuroimmunology, and descriptive/diagnostic
clinical science. Findings from these studies will provide clues for more effective therapies.
Tourette Syndrome Association 42-40 Bell Boulevard Suite 205 Bayside, NY 11361-2820 ts@tsa-usa.org http://tsa-usa.org Tel: 718-224-2999 888-4-TOURET (486-8738) Fax: 718-279-9596 |
Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892
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Last updated July 15, 2008