Short Course on the Genetics and Epigenetics of Addiction
National Institute on Drug Abuse: Archived Video

Bethesda North Marriott Hotel & Conference Center
March 31-April 4, 2008

Monday, March 31, 2008

8:00-8:45 a.m.	Registration
8:45-9:00 a.m.	Welcome Nora D. Volkow, M.D. National Institute on Drug Abuse
9:00-9:15 a.m.	Introduction Jonathan Pollock, Ph.D. National Institute on Drug Abuse Joni Rutter, Ph.D. National Institute on Drug Abuse
9:15-10:15 a.m.	Genetics of Complex Diseases Robert K. Moyzis, Ph.D. University of California College of Medicine Lecture and Implementation
10:15-10:45 a.m.	Genetic Epidemiology of Substance Use Disorders: Role of Family Studies Kathleen Ries Merikangas, Ph.D. National Institute of Mental Health Lecture
10:45-11:00 a.m.	Break
11:00-11:30 a.m.	Genetic Epidemiology of Addictions: Data That Helps to Define Potential Genetic Architectures Pamela Madden, Ph.D. Washington University Lecture
11:30 a.m.-12:30 p.m.	Statistical Genetics Concepts and Approaches for Complex Disorders Nicholas J. Schork, Ph.D. University of California--San Diego Lecture and Implementation
12:30-1:45 p.m.	Lunch (on your own)
1:45-2:45 p.m.	Progress from HapMap to Genome-Wide Association Mark Daly, Ph.D. Massachusetts General Hospital Lecture and Implementation
2:45-3:45 p.m.	Genome-Wide Association for Addiction and Treatment Response Phenotypes: Concepts George R. Uhl, M.D., Ph.D. National Institute on Drug Abuse Lecture and Implementation
3:45-4:00 p.m.	Break
4:00-4:45 p.m.	Genetic Epidemiology of Addictions: Data That Helps to Define Potential Genetic Architectures Pamela Madden, Ph.D. Washington University Implementation
4:45-7:00 p.m.	Computer Lab

Tuesday, April 1, 2008
8:30-9:00 a.m.	Registration
9:00-10:00 a.m.	Genome-Wide Association Studies: Phenotype and Genotype Studies Laura Jean Bierut, M.D. Washington University School of Medicine Lecture and Implementation
10:00-10:15 a.m.	Break
10:15-11:15 a.m.	Bayesian Methods for Identifying Gene-Gene Interactions Marco F. Ramoni, Ph.D. Harvard Medical School Lecture and Implementation
11:15 a.m.-12:15 p.m.	Linkage Studies of Nicotine Dependence Ming D. Li, Ph.D. University of Virginia Lecture and Implementation
12:15-2:00 p.m.	Lunch (on your own)
2:00-3:00 p.m.	Strategies for Finding Genetic Loci Associated with Alcoholism Howard J. Edenberg, Ph.D. Indiana University School of Medicine Lecture and Implementation
3:00-6:00 p.m.	Computer Lab
6:00 p.m.	Adjournment

Wednesday, April 2, 2008
8:30-9:00 a.m.	Registration
9:00-10:00 a.m.	Studies of Multiple Addictions in Samples of Individuals with Overlapping Addiction Phenotypes: Concepts Joel Gelernter, M.D. Yale University School of Medicine Problems and Analysis Bao-Zhu Yang, Ph.D. Yale University School of Medicine
10:00-10:15 a.m.	Break
10:15-11:15 a.m.	Pharmacogenetics of Nicotine Metabolism and Dependence Neurobiology of Nicotine Addiction Gary Swan, Ph.D. SRI International Lecture and Implementation
11:15 a.m.-12:15 p.m.	Pharmacogenomics and Nicotine Dependence Treatment Caryn Lerman, Ph.D. Tobacco Use Research Center Lecture and Implementation
12:15-2:00 p.m.	Lunch (on your own)
2:00-3:00 p.m.	Application and Use of Genetics Databases Deanna Church, Ph.D. National Center for Biotechnology Information Lecture and Implementation
3:00-6:00 p.m.	Computer Lab
6:00 p.m.	Adjournment

Thursday, April 3, 2008
8:30-9:00 a.m.	Registration
9:00-10:00 a.m.	Decode's Study of Nicotine Dependence: A Genome-Wide Association Study Thorgeir E. Thorgeirsson, Ph.D. deCODE Genetics Lecture and Implementation
10:00-10:15 a.m.	Break
10:15-11:15 a.m.	CNV Analysis of Complex Disorders Charles Lee, Ph.D. Brigham and Women's Hospital Lecture and Implementation
11:15 a.m.-12:15 p.m.	Using Bioinformatics to Prioritize Genetic Variants for Addiction Scott F. Saccone, Ph.D. Washington University School of Medicine Lecture and Implementation
12:15-1:45 p.m.	Lunch (on your own)
1:45-2:45 p.m.	Maternal Care Programs Neuroendocrine Systems Through Effects on DNA Methylation Michael Meaney, Ph.D. Douglas Hospital Research Centre Lecture and Implementation
2:45-3:00 p.m.	Break
3:00-3:30 p.m.	SAS & Genomics Demonstration Lauren McIntyre North Carolina State University
3:30-4:00 p.m.	How to Design Promoter Primers for CHIP William Renthal University of Texas Southwestern Medical Center
4:00-6:30 p.m.	Computer Lab
6:30 p.m.	Adjournment

Friday, April 4, 2008
8:30-8:45 a.m.	Registration
8:45-9:45 a.m.	Microarray Data Analysis: A Brief Overview Lauren M. McIntyre, Ph.D. University of Florida Lecture and Implementation
9:45-10:45 a.m.	Epigenetics: Concepts Brian Strahl, Ph.D. University of North Carolina School of Medicine Lecture and Implementation
10:45-11:45 a.m.	Epigenetic Regulation in Drug Addiction Eric J. Nestler, M.D., Ph.D. University of Texas Southwestern Medical Center Lecture and Implementation
11:45 a.m.-1:15 p.m.	Lunch (on your own)
1:15-2:15 p.m.	Mapping Complex Traits in the Mouse: Concepts Abraham A. Palmer, Ph.D. University of Chicago Lecture and Implementation
2:15-2:45 p.m.	Summary Jonathan Pollock, Ph.D. National Institute on Drug Abuse Joni Rutter, Ph.D. National Institute on Drug Abuse
2:45-3:45 p.m.	Speakers available for questions (take-home homework provided)
3:45-5:00 p.m.	Computer Lab
5:00 p.m.	Adjournment