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apolizumab A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) | 1D1O Anti-lymphoma Antibody Monoclonal antibody 1D10 Monoclonal Antibody Hu1D10 | | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) | Remitogen | | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) | MOAB 1D10 MoAb Hu1D10 | | ![](https://webarchive.library.unt.edu/eot2008/20090513043719im_/http://www.cancer.gov/images/spacer.gif) |
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