 |
|
recombinant interleukin-18
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-18 (IL-18). Produced primarily by macrophages, IL-18 induces the production of interferon-gamma (IFN-gamma), and enhances the activity of natural killer (NK) and cytotoxic T lymphocytes (CTL). As a potential immunotherapeutic agent, IL-18 displays antitumor effects in vitro and in animal models. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | IFN-gamma-inducing factor
interferon-gamma-inducing factor | | | | Abbreviation: | | IL-18 | | | | Code name: | | SB-485232 | | |
|
|
