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Study of Ipilimumab and Dasatinib Combination Therapy in Patients With Chronic or Accelerated Chronic Myeloid Leukemia

Basic Trial Information
Trial Description
     Summary
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase ITreatmentApproved-not yet active18 and overPharmaceutical / IndustryCA184-033
NCT00732186

Trial Description

Summary

The purpose of the study is to assess the safety of ipilimumab and dasatinib combination therapy in patients with CML

Eligibility Criteria

Inclusion Criteria:

  • Ph+ CML on dasatinib therapy
  • Loss of cytogenetic or molecular response while on dasatinib therapy
  • On stable dose of dasatinib for a minimum of 12 weeks and with < 14 day interruption of treatment

Exclusion Criteria:

  • Blast crisis CML
  • Autoimmune disease
  • Uncontrolled or significant cardiovascular disease

Trial Contact Information

Trial Lead Organizations/Sponsors

Bristol-Myers Squibb Company - New York

Bristol-Myers SquibbStudy Director

For participation information at a USA site use a phone number below. For site information outside the USA please email:
  Email: Clinical.Trials@bms.com

First line of email MUST contain NCT# & Site#. Only trial sites that are recruiting have contact information at this time.

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT00732186
Information obtained from ClinicalTrials.gov on April 23, 2009

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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