1.	Pre-Operative Chemo (CPT11, Cisplatin), Radiotherapy, Plus Surgery for Resectable Esophageal Cancer Phase: Phase III, Phase II Type: Treatment Status: Closed Age: 18 and over Sponsor: Other Protocol IDs: 02-0484-C, NCT00160875
2.	Phase II/III Trial of CPT-11/5-FU/l-LV Versus CPT-11/TS-1 as Second Line Chemotherapy of Unresectable Colorectal Cancer Phase: Phase III, Phase II Type: Treatment Status: Closed Age: 20 to 75 Sponsor: Pharmaceutical / Industry Protocol IDs: 01023010 / TOP-003, NCT00284258
3.	Phase III Randomized Study of Irinotecan vs Irinotecan/Fluorouracil/Leucovorin vs Fluorouracil/Leucovorin for Untreated Metastatic Colorectal Cancer (Summary Last Modified 12/98) Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: MSKCC-95051, P-UPJOHN-MSKCC-95051, NCI-V96-0913
4.	Phase III Randomized Study of Leucovorin Calcium Plus Fluorouracil With Either Irinotecan or Oxaliplatin in Patients With Recurrent Metastatic Colorectal Cancer (Summary Last Modified 05/2000) Phase: Phase III Type: Treatment Status: Closed Age: 18 to 75 Sponsor: Pharmaceutical / Industry Protocol IDs: FRE-GERCOR-C97-3/CPTF308, FRE-C97-3/CPTF301, FRE-C97-3/CPTF308, RP-FRE-C97-3/CPTF308, EU-97044, NCT00003260
5.	Phase III Randomized Study of Fluorouracil and Leucovorin Calcium With or Without Irinotecan Following Curative Resection in Patients With Stage III Colon Cancer Phase: Phase III Type: Treatment Status: Completed Age: 18 and over Sponsor: NCI Protocol IDs: CLB-89803, CAN-NCIC-CO15, E-89803, NCCTG-C89803, SWOG-C89803, NCT00003835, C89803, CO15
6.	Phase III Randomized Study of High-Dose Fluorouracil and Leucovorin Calcium With or Without Irinotecan in Patients With Metastatic Adenocarcinoma of the Colon or Rectum (Summary Last Modified 02/2002) Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Protocol IDs: EORTC-40986, NCT00004885
7.	Phase III Randomized Study of Irinotecan Versus Oxaliplatin, Fluorouracil, and Leucovorin Calcium in Patients With Advanced Colorectal Cancer Previously Treated With Fluorouracil Phase: Phase III Type: Treatment Status: Completed Age: 18 and over Sponsor: NCI Protocol IDs: NCCTG-N9841, ECOG-N9841, SWOG-N9841, NCT00005036, N9841
8.	Phase III Randomized Study of Adjuvant Leucovorin Calcium and Fluorouracil With or Without Irinotecan in Patients With Resected Stage III Colon Cancer at High Risk of Recurrence Phase: Phase III Type: Treatment Status: Closed Age: 18 to 75 Sponsor: Other Protocol IDs: FRE-FNCLCC-ACCORD-2, FFCD-9802, EU-20014, NCT00005979
9.	Phase III Study of Fluorouracil, Leucovorin Calcium, and Irinotecan in Patients With Metastatic, Locally Advanced, or Recurrent Colorectal Cancer Phase: Phase III Type: Treatment Status: Completed Age: Not specified Sponsor: NCI Protocol IDs: CLB-9864, E-C9864, NCT00006103, C9864
10.	Phase III Randomized Study of Octreotide in the Prevention of Diarrhea Induced By Irinotecan in Patients With Metastatic Colorectal Cancer Phase: Phase III Type: Supportive care, Treatment Status: Closed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: NOVARTIS-CSMS995US05, NCT00006269
11.	Phase III Randomized Study of Fluorouracil With Leucovorin Calcium and Either Irinotecan or Oxaliplatin in Patients With Unresectable Metastatic Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Other Protocol IDs: MRC-CR08-FOCUS, EU-20038, ISRCTN79877428, NCT00008060
12.	Phase III Randomized Study of Bevacizumab (rhuMAb VEGF) With Fluorouracil and Leucovorin Calcium With or Without Irinotecan in Patients With Metastatic Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: GENENTECH-AVF2107g, UCLA-0008022, NCT00012233
13.	Phase III Randomized Study of Irinotecan With or Without Oxaliplatin in Patients With Metastatic Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: SANOFI-EFC4585, NCT00012389
14.	Phase III Randomized Study of Regional and Systemic Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Patients With Unresectable Colorectal Cancer Metastatic to the Liver Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: NCI Protocol IDs: NCI-01-C-0093, NCT00020501
15.	Phase III Randomized Study of Fluorouracil, Leucovorin Calcium, and Irinotecan With or Without SU5416 in Patients With Previously Untreated Metastatic Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: NCI, Pharmaceutical / Industry Protocol IDs: UCLA-001003701, SUGEN-SU5416.035, NCI-G01-1980, NCT00021281
16.	Phase III Randomized Study of Irinotecan, Fluorouracil, and Leucovorin Calcium With or Without Hepatic Chemoembolization in Patients With Adenocarcinoma of the Colon or Rectum Metastatic to the Liver Phase: Phase III Type: Treatment Status: Completed Age: 18 and over Sponsor: NCI Protocol IDs: ACRIN-6655, NCT00023868
17.	Phase III Randomized Study of Adjuvant Fluorouracil and Leucovorin Calcium With or Without Irinotecan in Patients With Resected Stage III Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 to 75 Sponsor: Pharmaceutical / Industry Protocol IDs: RP-64174-V-307, EORTC-40993, PETACC-3, NCT00026273
18.	Phase III Randomized Study of Cisplatin and Irinotecan Versus Cisplatin and Etoposide in Patients With Extensive Stage Small Cell Lung Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: NCI Protocol IDs: SWOG-S0124, NCCTG-S0124, CALGB-S0124, S0124, NCT00045162
19.	Phase III Randomized Study of Irinotecan and Capecitabine Versus Irinotecan, Leucovorin Calcium, and Fluorouracil With Versus Without Celecoxib in Patients With Metastatic Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: Other Protocol IDs: EORTC-40015, NCT00064181
20.	Phase III Randomized Study of Adjuvant Irinotecan, Fluorouracil, and Leucovorin Calcium Versus Oxaliplatin, Fluorouracil, and Leucovorin Calcium Versus Fluorouracil and Leucovorin Calcium in Patients With Stage II or III Rectal Cancer Receiving Combined Radiotherapy and Fluorouracil Either Preoperatively or Postoperatively Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: NCI Protocol IDs: ECOG-E3201, E3201, NCT00068692
21.	Phase III Randomized Study of Fluorouracil and Leucovorin Calcium With Irinotecan or Oxaliplatin and With or Without Cetuximab in Patients With Previously Untreated Metastatic Adenocarcinoma of the Colon or Rectum Phase: Phase III Type: Treatment Status: Closed Age: 18 and over Sponsor: NCI Protocol IDs: CALGB-80203, NCT00077233
22.	Study of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal Cancer Phase: Phase III Type: Treatment Status: Completed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: CA225006, NCT00063141
23.	Phase III Randomized Study of Adjuvant Chemotherapy Comprising Fluorouracil and Irinotecan With or Without Leucovorin Calcium Versus No Adjuvant Therapy in Patients With Resected Stage II Adenocarcinoma of the Colon Phase: Phase III Type: Treatment Status: Closed Age: 18 to 75 Sponsor: Other Protocol IDs: FFCD-EORTC-40012, EORTC-40012, PETACC-4, NCT00091312
24.	PACCE: Panitumumab Advanced Colorectal Cancer Evaluation Study Phase: Phase III Type: Treatment Status: Completed Age: 18 and over Sponsor: Pharmaceutical / Industry Protocol IDs: 20040249, NCT00115765
25.	Comparing Irinotecan and 5 FU/FA To 5-FU/FA After Resection Of Liver Metastases For Colorectal Cancer Phase: Phase III Type: Treatment Status: Closed Age: 18 to 75 Sponsor: Pharmaceutical / Industry Protocol IDs: CPT-GMA-301, A5961076, NCT00143403