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N-methylformamide A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | formylmethylamine monomethylformamide | | | Abbreviation: | | NMF | | | Code names: | | EK 7011 X 188 | | |
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