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iodine I 131 tositumomab A monoclonal antibody directed against the CD20 protein expressed on the surface of B-lymphocytes and radiolabeled with the radioisotope iodine I 131 with potential antineoplastic activity. Iodine I 131 tositumomab binds to and selectively delivers cyctotoxic radiation to CD20-expressing B-lymphocytes, thereby minimizing systemic radiotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090509212757im_/http://www.cancer.gov/images/spacer.gif) | 131-I-anti-B1 antibody 131-I-anti-B1 monoclonal antibody iodine I 131 MOAB anti-B1 iodine I 131 monoclonal antibody anti-B1 iodine-131 anti-B1 antibody iodine-131 anti-CD20 monoclonal antibody | | ![](https://webarchive.library.unt.edu/eot2008/20090509212757im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20090509212757im_/http://www.cancer.gov/images/spacer.gif) | I131-MOAB-B1 | | ![](https://webarchive.library.unt.edu/eot2008/20090509212757im_/http://www.cancer.gov/images/spacer.gif) |
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