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perfosfamide
The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | hydroperoxycyclophosphamide | | | | US brand name: | | Pergamid | | | | Abbreviation: | | 4-HC | | | | Chemical structure names: | | - 2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
- 4'-hydroperoxycyclophosphamide
- 4-Pergamid
- cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxide
- cis-4-hydroperoxycyclophosphamide
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