 |
|
chloroquinoxaline sulfonamide
A chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and potential immunosuppressive activity. Chloroquinoxaline sulfonamide poisons topoisomerase II alpha and topoisomerase II beta, thereby causing double-stranded breaks in DNA, accumulation of unrepaired DNA, and apoptosis. This agent also exhibits lymphotoxicity by inhibiting lymphocyte activation in a cell cycle-specific manner. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | chlorosulfaquinoxaline
chlorsulfaquinoxaline | | | | Abbreviation: | | CQS | | | | Chemical structure name: | | benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)- | | |
|
|
