Hematopoietic Stem Cell Transplantation: Transformation of a Field (NIH-Only) |
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| Launch in standalone player | |
| Air date: | Tuesday, March 31, 2009, 8:00:00 AM |
| Category: | NCI CCR Grand Rounds (NIH Only) |
| Description: | Dr. Bishop received his M.D. from the University of Illinois College of Medicine in Chicago. He completed clinical training in internal medicine at Northwestern University and a fellowship in hematology and oncology at Loyola University Medical Center. He was an assistant professor of medicine at the University of Kentucky Medical Center before accepting a position at the University of Nebraska Medical Center to serve as director of the Leukemia and Allogeneic Stem Cell Transplantation Programs. Dr. Bishop joined the National Cancer Institute in March 1999 to serve as the clinical head of the Stem Cell Transplantation Program. Dr. Bishop currently serves as head of the Transplant Clinical Research Section in the NCI Experimental Transplantation and Immunology Branch. The primary goal of the Clinical Transplantation Therapy Program is to develop and conduct novel clinical trials in hematopoietic stem cell transplantation. Particular areas of interest within the program include the therapeutic use of T cells to enhance engraftment T-cell reconstitution as well as accentuate graft-versus-tumor effects. In addition, the program focuses on methods to prevent and treat recurrent disease following allogeneic stem cell transplantation, with a primary focus on B-cell malignancies. Dr. Bishop has authored or co-authored more than 120 peer-reviewed articles and over 20 book chapters relative to the fields of hematologic malignancies and hematopoietic stem cell transplantation. In 2003, he received the National Institutes of Health Distinguished Clinical Teacher Award. He received tenure as senior investigator at NIH in 2007.
SELECTED REFERENCES: 1. Bishop MR, Whit-Shan Hou J, Wilson WH, Steinberg SM, Odom J, Castro K, Kasten-Sportes C, Gea-Banacloche J, Marchigiani D, Gress R, Fowler DH. Establishment of early donor engraftment after reduced-intensity allogeneic hematopoietic stem cell transplantation to potentiate the graft-versus-lymphoma effect against refractory lymphomas. Biol Blood Marrow Transplant 2003;9:162–9. 2. Fowler DH, Odom J, Steinberg SM, Chow CK, Foley J, Kogan Y, Hou J, Gea-Banacloche J, Sportes C, Pavletic S, Leitman S, Read EJ, Carter C, Mair R, Beatty GL, Vonderheide RH, Levine BL, June CH, Gress RE, Bishop MR. Phase I clinical trial of hematopoietic stem cell allograft augmentation with co-stimulated, IL-4 polarized donor CD4+ T cells. Biol Blood Marrow Transplant 2006;12:1150–60. 3. Dean RM, Fry T, Mackall C, Steinberg SM, Hakim F, Fowler D, Odom J, Foley J, Gress R, Bishop MR. Association of serum interleukin-7 levels with the development of acute graft-versus-host disease. J Clin Oncol 2008;26:5735–41. NCI’s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx |
| Author: | Michael R. Bishop, M.D. |
| Runtime: | 60 minutes |
| CIT File ID: | 15001 |
| CIT Live ID: | 7524 |
| Permanent link: | http://videocast.nih.gov/launch.asp?15001 |