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decitabine
A cytidine antimetabolite analogue with potential antineoplastic activity. Decitabine incorporates into DNA and inhibits DNA methyltransferase, resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | 5-aza-dCyd
deoxyazacytidine
dezocitidine | | | | US brand name: | | Dacogen | | | | Abbreviations: | | 5AZA
DAC | | | | Chemical structure names: | | - 2'-deoxy-5-azacytidine
- 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one
- 5-aza-2'-deoxycytidine
- 5-aza-2-deoxycytidine
- 5-azadeoxycytidine
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