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paclitaxel-loaded polymeric micelle
A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer miceller nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Genexol-PM | | |
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