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University of California San Francisco

Breast Cancer & the Environmental Research Centers

University of California, San Francisco - Bay Area
Center Director: Robert A. Hiatt, M.D., Ph.D. Exit NIEHS

This proposal from an expert set of investigators would form the basis of the Bay Area Breast Cancer and the Environment Research Center to address the concerns about environmental impact on mammary gland development during critical windows of exposure. Novel approaches to studying the impact of environmental exposures on the interactions between epithelial cells and stromal cells were proposed. Normal and cancer-prone mice will be examined during varied stages of development to determine the effects of exposure to multiple stressors and will attempt to develop more sensitive screens for carcinogenicity. In concert with these investigations, an epidemiological multiethnic study will examine and follow through puberty a cohort of 7 – 8 year old girls from the Kaiser Foundation Health Plan. The Community Outreach and Translation Core will involve organizations in San Francisco and Marin County and will provide interactions with the engaged community and provide a means for feedback of concerns to the investigators.


  • California Dept. of Health Services
  • Kaiser Permanente of Northern California
  • Lawrence Berkeley National Laboratory
  • Marin County Dept. of Health & Human Services
  • Roswell Park Cancer Center
  • University of Michigan
  • Zero Breast Cancer

Community Partners:

  • Bay Area Breast Cancer SPORE Advocacy Group
  • Bayview Hunters Point Health & Environmental Assessment Task Force
  • Breast Cancer Fund
  • Community Health Agency
  • Zero Breast Cancer (formerly Marin Breast Cancer Watch)

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Last Reviewed: June 20, 2007