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pyroxamide A synthetic derivative of hydroxamic acid with antineoplastic properties, Pyroxamide inhibits histone deacetylases involved in transcription; induces hyperacetylation of core histones, modulating chromatin structure and affecting transcription of some genes that inhibit tumor growth; and induces growth arrest and apoptosis. Pyroxamide is used in clinical studies for cancer chemotherapy. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Chemical structure name: | | Suberoyl-3-aminopyridineamide Hydroxamic Acid | | |
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