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prednisone
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Delta(1)-Cortisone
deltacortisone
deltadehydrocortisone
metacortandracin
PRD
Prednisonum | | | | US brand names: | | Delta-Dome
Deltasone
Liquid Pred
Lisacort
Meticorten
Orasone
Prednicen-M
Sk-Prednisone
Sterapred | | | | Foreign brand names: | | Adasone
Cortancyl
Dacortin
DeCortin
Decortisyl
Decorton
Deltacortene
Deltison
Deltra
Econosone
Meprosona-F
Ofisolona
Panafcort
Panasol-S
Paracort
Predeltin
Predicor
Predicorten
Prednicort
Prednidib
Prednilonga
Predniment
Prednitone
Promifen
Servisone | | | | Abbreviation: | | PRED | | | | Chemical structure names: | | - 1;2-dehydrocortisone
- 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
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