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sorafenib tosylate
The tosylate salt of sorafenib, a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF/MEK/ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR-2/PDGFR-beta signaling cascade, thereby blocking tumor angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | BAY 43-9006
BAY 43-9006 Tosylate Salt | | | | US brand name: | | Nexavar | | | | Abbreviation: | | SFN | | | | Code name: | | BAY 54-9085 | | | | Chemical structure names: | | - 2-pyridinecarboxamide, 4-[4-[[[[4-chloro-3- trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-
- 4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate tosylate
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