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staphylococcus aureus protein A A protein that resides in the microbial wall of staphylococcus aureus and interferes with opsonization by binding to the Fc portion of immunoglobulin. The protein has a deleterious effect on the epithelial cells that line the respiratory tract, and plays a role in the induction of pneumonia. Protein A also initiates polymorphonuclear cell migration into airway passages via TNFR1 activation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090509173351im_/http://www.cancer.gov/images/spacer.gif) | S. aureus protein A Staph. Protein A | | ![](https://webarchive.library.unt.edu/eot2008/20090509173351im_/http://www.cancer.gov/images/spacer.gif) |
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