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Alternative Names Return to top
Tertiary Lyme disease; Stage 3 Lyme disease; Late persistent Lyme diseaseDefinition Return to top
Chronic persistent Lyme disease is a late stage of an inflammatory disease caused by Borrelia burgdorferi bacteria. It is also called Stage 3, or tertiary, Lyme disease.
See also:
Causes Return to top
Lyme disease is transmitted by the bite of a deer tick. Tertiary Lyme disease occurs months to years after the initial infection with Lyme disease.
Symptoms Return to top
Chronic persistent Lyme disease can affect the skin, brain and nervous system, and muscles, bones, and cartilage.
Symptoms include:
Other symptoms that may be associated with this disease:
Exams and Tests Return to top
A blood test can be done to check for antibodies to the bacteria that cause Lyme disease. The most common one used is the ELISA for Lyme disease test. A Western blot test is done to confirm ELISA results.
A spinal tap will be abnormal if the patient has central nervous system symptoms related to the disease.
Treatment Return to top
Antibiotics are given to fight the infection. Medications sometimes need to be given through a vein (intravenously).
Treating patients for longer periods of time is generally not thought to be helpful, even if symptoms do not go away.
Outlook (Prognosis) Return to top
Arthritis symptoms may not get better with treatment. Other symptoms should improve with treatment.
Rarely, a person will continue to have symptoms that can sometimes interfere with daily life or activities. Some people call this post-Lyme disease syndrome. Unfortunately, there is no effective treatment for people with these symptoms.
Possible Complications Return to top
Arthritis symptoms may continue.
When to Contact a Medical Professional Return to top
Call your health care provider if you develop symptoms, especially if you have had Lyme disease before, or live or travel in high-risk areas.
Prevention Return to top
Early diagnosis and appropriate antibiotic treatment for primary Lyme disease is the most effective way to prevent tertiary Lyme disease.
Here are some tips for preventing primary Lyme disease:
When walking or hiking in wooded or grassy areas:
Check yourself and your pets frequently during and after your walk or hike.
Ticks that carry Lyme disease are so small that they are very hard to see. After returning home, remove your clothes and thoroughly inspect all skin surface areas, including your scalp.
If possible, ask someone to help you examine your body for ticks. Adults should carefully examine children.
References Return to top
Feder HM Jr, Johnson BJ, O'Connell S, Shapiro ED, Steere AC, Wormser GP. Ad Hoc International Lyme Disease Group. A critical appraisal of "chronic Lyme disease." N Engl J Med. 2007;357:1422-1430.
Halperin JJ, Shapiro ED, Logigian E, Belman AL, Dotevall L, Wormser GP, et al. Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2007;69:91-102.
Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC, Klempner MS, et al. The clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2006;43:1089:1134.
Update Date: 5/20/2008 Updated by: Jatin M. Vyas, PhD, MD, Instructor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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Page last updated: 25 September 2008 |