udenafil| A benzenesulfonamide derivative with vasodilatory activity. Udenafil selectively inhibits phosphodiesterase type 5 (PDE5), thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis; inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection. This agent does not significantly inhibit the PDE11 isozyme; PDE11 inhibition may be associated with significant myalgia. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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Ultandren| (Other name for: fluoxymesterone) |
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Ultane| (Other name for: sevoflurane) |
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Ultiva| (Other name for: remifentanil hydrochloride) |
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ultralow-molecular-weight heparin AVE5026| An ultralow-molecular-weight heparin (ULMWH) (Mw: 2000-3000 daltons) consisting of a polydisperse mixture of oligomeric heparin fragments with potential anticoagulant activity. Ultralow-molecular-weight heparin AVE5026 binds to and activates antithrombin III (ATIII), which may result in the inhibition of activated factor Xa and, to a much lesser extent, factor IIa (thrombin) and so the inhibition of fibrin formation. Compared to low-molecular-weight heparins (LMWHs), AVE5026 exhibits an even higher ratio of anti-Factor Xa to anti-Factor IIa activity (>30:1). Compared to unfractionated heparins, the use of LMWHs is associated with lower incidences of major bleeding, osteoporosis and heparin-induced thrombocytopenia. Like LMWHs, this agent may inhibit tumor growth by regulating angiogenesis and apoptosis. AVE5026 is prepared by partial depolymerization of unfractionated porcine mucosal heparin. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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Unasyn| (Other name for: ampicillin sodium/sulbactam sodium) |
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Uniphyl| (Other name for: theophylline) |
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uridine| A nucleoside consisting of uracil and D-ribose and a component of RNA. Uridine has been studied as a rescue agent to reduce the toxicities associated with 5-fluorouracil (5-FU), thereby allowing the administration of higher doses of 5-FU in chemotherapy regimens. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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URLC10 peptide/Montanide ISA51 vaccine| A cancer vaccine containing URLC10 (up-regulated lung cancer 10) epitopes with potential immunostimulatory and antineoplastic activities. Upon administration, URL peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells. Up-regulated in lung and esophageal cancers, the function of URLC10 is unknown. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine| A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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Urolene Blue| (Other name for: methylene blue) |
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Uroxatrol| (Other name for: alfuzosin hydrochloride) |
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URSO| (Other name for: ursodiol) |
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ursodiol| A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus) |
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Utimox| (Other name for: amoxicillin) |
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Uvadex| (Other name for: methoxsalen) |
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Uvidem| (Other name for: autologous dendritic cell-allogeneic melanoma tumor cell lysate vaccine) |
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