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bupivacaine hydrochloride A long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20090509164859im_/http://www.cancer.gov/images/spacer.gif) | Bupivacaine | | ![](https://webarchive.library.unt.edu/eot2008/20090509164859im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509164859im_/http://www.cancer.gov/images/spacer.gif) | Sensorcaine-MPF | | ![](https://webarchive.library.unt.edu/eot2008/20090509164859im_/http://www.cancer.gov/images/spacer.gif) |
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