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valdecoxib A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) | Bextra | | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) | Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) | SC 65872 | | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) | 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide | | ![](https://webarchive.library.unt.edu/eot2008/20090509164856im_/http://www.cancer.gov/images/spacer.gif) |
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