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Volume 36(7);  April 2008
Molecular Biology
PDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1
Prabhat Kumar Purbey, Sunita Singh, P. Pavan Kumar, Sameet Mehta, K. N. Ganesh, Debashis Mitra, and Sanjeev Galande
Nucleic Acids Res. 2008 April; 36(7): 2107–2122. Published online 2008 April. doi: 10.1093/nar/gkm1151.
PMCID: PMC2367706
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein
Jeffrey M. Chen, Huiping Ren, James E. Shaw, Yu Jing Wang, Ming Li, Andrea S. Leung, Vanessa Tran, Nicolas M. Berbenetz, Dana Kocíncová, Christopher M. Yip, Jean-Marc Reyrat, and Jun Liu
Nucleic Acids Res. 2008 April; 36(7): 2123–2135. Published online 2008 April. doi: 10.1093/nar/gkm1162.
PMCID: PMC2367712
Eukaryotic Y-family polymerases bypass a 3-methyl-2′-deoxyadenosine analog in vitro and methyl methanesulfonate-induced DNA damage in vivo
Brian S. Plosky, Ekaterina G. Frank, David A. Berry, Graham P. Vennall, John P. McDonald, and Roger Woodgate
Nucleic Acids Res. 2008 April; 36(7): 2152–2162. Published online 2008 April. doi: 10.1093/nar/gkn058.
PMCID: PMC2367705
Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase γ replication fidelity
Zachary F. Pursell, J. Tyson McDonald, Christopher K. Mathews, and Thomas A. Kunkel
Nucleic Acids Res. 2008 April; 36(7): 2174–2181. Published online 2008 April. doi: 10.1093/nar/gkn062.
PMCID: PMC2367704
Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers
Koji Tsumagari, Lixin Qi, Kesmic Jackson, Chunbo Shao, Michelle Lacey, Janet Sowden, Rabi Tawil, Vettaikorumakankav Vedanarayanan, and Melanie Ehrlich
Nucleic Acids Res. 2008 April; 36(7): 2196–2207. Published online 2008 April. doi: 10.1093/nar/gkn055.
PMCID: PMC2367708
Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro
Hiroaki Tachiwana, Akihisa Osakabe, Hiroshi Kimura, and Hitoshi Kurumizaka
Nucleic Acids Res. 2008 April; 36(7): 2208–2218. Published online 2008 April. doi: 10.1093/nar/gkn060.
PMCID: PMC2367731
LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated
Brian J. Krueger, Célia Jeronimo, Bibhuti Bhusan Roy, Annie Bouchard, Charlotte Barrandon, Sarah A. Byers, Courtney E. Searcey, Jeffrey J. Cooper, Olivier Bensaude, Éric A. Cohen, Benoit Coulombe, and David H. Price
Nucleic Acids Res. 2008 April; 36(7): 2219–2229. Published online 2008 April. doi: 10.1093/nar/gkn061.
PMCID: PMC2367717
Binding of sulphonated indigo derivatives to RepA-WH1 inhibits DNA-induced protein amyloidogenesis
Fátima Gasset-Rosa, María Jesús Maté, Cristina Dávila-Fajardo, Jerónimo Bravo, and Rafael Giraldo
Nucleic Acids Res. 2008 April; 36(7): 2249–2256. Published online 2008 April. doi: 10.1093/nar/gkn067.
PMCID: PMC2367726
Nucleocapsid mutations turn HIV-1 into a DNA-containing virus
Laurent Houzet, Zakia Morichaud, Ludovic Didierlaurent, Delphine Muriaux, Jean-Luc Darlix, and Marylène Mougel
Nucleic Acids Res. 2008 April; 36(7): 2311–2319. Published online 2008 April. doi: 10.1093/nar/gkn069.
PMCID: PMC2367716
Position effect variegation and imprinting of transgenes in lymphocytes
Adam Williams, Nicola Harker, Eleni Ktistaki, Henrique Veiga-Fernandes, Kathleen Roderick, Mauro Tolaini, Trisha Norton, Keith Williams, and Dimitris Kioussis
Nucleic Acids Res. 2008 April; 36(7): 2320–2329. Published online 2008 April. doi: 10.1093/nar/gkn085.
PMCID: PMC2367730
Molecular dissection of mRNA poly(A) tail length control in yeast
Nicolas Viphakone, Florence Voisinet-Hakil, and Lionel Minvielle-Sebastia
Nucleic Acids Res. 2008 April; 36(7): 2418–2433. Published online 2008 April. doi: 10.1093/nar/gkn080.
PMCID: PMC2367721
An upstream open reading frame within an IRES controls expression of a specific VEGF-A isoform
Amandine Bastide, Zeineb Karaa, Stéphanie Bornes, Corinne Hieblot, Eric Lacazette, Hervé Prats, and Christian Touriol
Nucleic Acids Res. 2008 April; 36(7): 2434–2445. Published online 2008 April. doi: 10.1093/nar/gkn093.
PMCID: PMC2367723
RNA
Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect
Kumiko Ui-Tei, Yuki Naito, Shuhei Zenno, Kenji Nishi, Kenji Yamato, Fumitaka Takahashi, Aya Juni, and Kaoru Saigo
Nucleic Acids Res. 2008 April; 36(7): 2136–2151. Published online 2008 April. doi: 10.1093/nar/gkn042.
PMCID: PMC2367719
Human branch point consensus sequence is yUnAy
Kaiping Gao, Akio Masuda, Tohru Matsuura, and Kinji Ohno
Nucleic Acids Res. 2008 April; 36(7): 2257–2267. Published online 2008 April. doi: 10.1093/nar/gkn073.
PMCID: PMC2367711
Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans
Mirko Cevec, Christophe Thibaudeau, and Janez Plavec
Nucleic Acids Res. 2008 April; 36(7): 2330–2337. Published online 2008 April. doi: 10.1093/nar/gkn088.
PMCID: PMC2367737
Requirements for gene silencing mediated by U1 snRNA binding to a target sequence
Xabi Abad, Maria Vera, Stephen P. Jung, Evelyn Oswald, Inés Romero, Vaibhav Amin, Puri Fortes, and Samuel I. Gunderson
Nucleic Acids Res. 2008 April; 36(7): 2338–2352. Published online 2008 April. doi: 10.1093/nar/gkn068.
PMCID: PMC2367729
Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element
Dominique L. Ouellet, Isabelle Plante, Patricia Landry, Corinne Barat, Marie-Ève Janelle, Louis Flamand, Michel J. Tremblay, and Patrick Provost
Nucleic Acids Res. 2008 April; 36(7): 2353–2365. Published online 2008 April. doi: 10.1093/nar/gkn076.
PMCID: PMC2367715
Structural Biology
Towards a molecular dynamics consensus view of B-DNA flexibility
Alberto Pérez, Filip Lankas, F. Javier Luque, and Modesto Orozco
Nucleic Acids Res. 2008 April; 36(7): 2379–2394. Published online 2008 April. doi: 10.1093/nar/gkn082.
PMCID: PMC2367714
Survey and Summary
Specificity of DNA microarray hybridization: characterization, effectors and approaches for data correction
Hinanit Koltai and Carmiya Weingarten-Baror
Nucleic Acids Res. 2008 April; 36(7): 2395–2405. Published online 2008 April. doi: 10.1093/nar/gkn087.
PMCID: PMC2367720
Genomics
The complete nucleotide sequences of the five genetically distinct plastid genomes of Oenothera, subsection Oenothera: I. Sequence evaluation and plastome evolution
Stephan Greiner, Xi Wang, Uwe Rauwolf, Martina V. Silber, Klaus Mayer, Jörg Meurer, Georg Haberer, and Reinhold G. Herrmann
Nucleic Acids Res. 2008 April; 36(7): 2366–2378. Published online 2008 April. doi: 10.1093/nar/gkn081.
PMCID: PMC2367718
Methods Online
Elevated α-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease
Jan Gründemann, Falk Schlaudraff, Olga Haeckel, and Birgit Liss
Nucleic Acids Res. 2008 April; 36(7): e38. Published online 2008 April. doi: 10.1093/nar/gkn084.
PMCID: PMC2367701
High-resolution array comparative genomic hybridization of single micrometastatic tumor cells
Christine Fuhrmann, Oleg Schmidt-Kittler, Nikolas H. Stoecklein, Karina Petat-Dutter, Christian Vay, Kerstin Bockler, Richard Reinhardt, Thomas Ragg, and Christoph A. Klein
Nucleic Acids Res. 2008 April; 36(7): e39. Published online 2008 April. doi: 10.1093/nar/gkn101.
PMCID: PMC2367728
Labeling of unique sequences in double-stranded DNA at sites of vicinal nicks generated by nicking endonucleases
Heiko Kuhn and Maxim D. Frank-Kamenetskii
Nucleic Acids Res. 2008 April; 36(7): e40. Published online 2008 April. doi: 10.1093/nar/gkn107.
PMCID: PMC2373456
wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data
Patrick Cahan, Laura E. Godfrey, Peggy S. Eis, Todd A. Richmond, Rebecca R. Selzer, Michael Brent, Howard L. McLeod, Timothy J. Ley, and Timothy A. Graubert
Nucleic Acids Res. 2008 April; 36(7): e41. Published online 2008 April. doi: 10.1093/nar/gkn110.
PMCID: PMC2367727
Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection
Lasse S. Kristensen, Thomas Mikeska, Michael Krypuy, and Alexander Dobrovic
Nucleic Acids Res. 2008 April; 36(7): e42. Published online 2008 April. doi: 10.1093/nar/gkn113.
PMCID: PMC2367707
Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions
Katleen De Preter, Roland Barriot, Frank Speleman, Jo Vandesompele, and Yves Moreau
Nucleic Acids Res. 2008 April; 36(7): e43. Published online 2008 April. doi: 10.1093/nar/gkn114.
PMCID: PMC2367735
Generation of ρ0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses
Alexandra Kukat, Christian Kukat, Jan Brocher, Ingo Schäfer, Georg Krohne, Ian A. Trounce, Gaetano Villani, and Peter Seibel
Nucleic Acids Res. 2008 April; 36(7): e44. Published online 2008 April. doi: 10.1093/nar/gkn124.
PMCID: PMC2367725
Computational Biology
Phylogenetic classification of short environmental DNA fragments
Lutz Krause, Naryttza N. Diaz, Alexander Goesmann, Scott Kelley, Tim W. Nattkemper, Forest Rohwer, Robert A. Edwards, and Jens Stoye
Nucleic Acids Res. 2008 April; 36(7): 2230–2239. Published online 2008 April. doi: 10.1093/nar/gkn038.
PMCID: PMC2367736
Accurate statistical model of comparison between multiple sequence alignments
Ruslan I. Sadreyev and Nick V. Grishin
Nucleic Acids Res. 2008 April; 36(7): 2240–2248. Published online 2008 April. doi: 10.1093/nar/gkn065.
PMCID: PMC2367703
Magnitude and direction of DNA bending induced by screw-axis orientation: influence of sequence, mismatches and abasic sites
Jeremy Curuksu, Krystyna Zakrzewska, and Martin Zacharias
Nucleic Acids Res. 2008 April; 36(7): 2268–2283. Published online 2008 April. doi: 10.1093/nar/gkm1135.
PMCID: PMC2367702
Empirical comparison of ab initio repeat finding programs
Surya Saha, Susan Bridges, Zenaida V. Magbanua, and Daniel G. Peterson
Nucleic Acids Res. 2008 April; 36(7): 2284–2294. Published online 2008 April. doi: 10.1093/nar/gkn064.
PMCID: PMC2367713
PROMALS3D: a tool for multiple protein sequence and structure alignments
Jimin Pei, Bong-Hyun Kim, and Nick V. Grishin
Nucleic Acids Res. 2008 April; 36(7): 2295–2300. Published online 2008 April. doi: 10.1093/nar/gkn072.
PMCID: PMC2367709
PARTS: Probabilistic Alignment for RNA joinT Secondary structure prediction
Arif Ozgun Harmanci, Gaurav Sharma, and David H. Mathews
Nucleic Acids Res. 2008 April; 36(7): 2406–2417. Published online 2008 April. doi: 10.1093/nar/gkn043.
PMCID: PMC2367733
SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines
Francesca Demichelis, Heidi Greulich, Jill A. Macoska, Rameen Beroukhim, William R. Sellers, Levi Garraway, and Mark A. Rubin
Nucleic Acids Res. 2008 April; 36(7): 2446–2456. Published online 2008 April. doi: 10.1093/nar/gkn089.
PMCID: PMC2367734
Nucleic Acid Enzymes
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences
Emmanuel Fajardo-Sanchez, François Stricher, Frédéric Pâques, Mark Isalan, and Luis Serrano
Nucleic Acids Res. 2008 April; 36(7): 2163–2173. Published online 2008 April. doi: 10.1093/nar/gkn059.
PMCID: PMC2367722
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease
Kirk Tevebaugh Ehmsen and Wolf-Dietrich Heyer
Nucleic Acids Res. 2008 April; 36(7): 2182–2195. Published online 2008 April. doi: 10.1093/nar/gkm1152.
PMCID: PMC2367710
Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence
Daniel A. Koster, Fabian Czerwinski, Ludovic Halby, Aurélien Crut, Pierre Vekhoff, Komaraiah Palle, Paola B. Arimondo, and Nynke H. Dekker
Nucleic Acids Res. 2008 April; 36(7): 2301–2310. Published online 2008 April. doi: 10.1093/nar/gkn035.
PMCID: PMC2367732
Corrigendum
The Molecule Pages Database
Brian Saunders, Stephen Lyon, Matthew Day, Brenda Riley, Emily Chenette, and Shankar Subramaniam
Nucleic Acids Res. 2008 April; 36(7): 2457. Published online 2008 April. doi: 10.1093/nar/gkn139.
PMCID: PMC2367724
Corrects: Brian Saunders, et al. The Molecule Pages database. Nucleic Acids Res. 2008 January; 36(Database issue): D700–D706.
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