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metformin hydrochloride The hydrochloride salt of the biguanide metformin with antihyperglycemic activity. Metformin decreases hepatic gluconeogenesis and intestinal absorption of glucose. This agent also increases the number and/or affinity of insulin receptors on muscle and adipose cells, increasing the sensitivity to insulin at receptor and post-receptor binding sites and increasing glucose uptake peripherally. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509155801im_/http://www.cancer.gov/images/spacer.gif) | Glucophage | | ![](https://webarchive.library.unt.edu/eot2008/20090509155801im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure names: | ![](https://webarchive.library.unt.edu/eot2008/20090509155801im_/http://www.cancer.gov/images/spacer.gif) | - 1,1-dimethylbiguanide hydrochloride
- N,N-dimethylimidodicarbonimidic diamide monohydrochloride
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