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modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20090509155139im_/http://www.cancer.gov/images/spacer.gif) | MVA-BN-HER2 vaccine | | ![](https://webarchive.library.unt.edu/eot2008/20090509155139im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509155139im_/http://www.cancer.gov/images/spacer.gif) | MVA-BN Breast | | ![](https://webarchive.library.unt.edu/eot2008/20090509155139im_/http://www.cancer.gov/images/spacer.gif) |
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