National Cancer Institute
U.S. National Institutes of Health | www.cancer.gov

NCI Home
Cancer Topics
Clinical Trials
Cancer Statistics
Research & Funding
News
About NCI
NCI Drug Dictionary
Page Options
Print This Page
More NCI Dictionaries
Dictionary of Cancer Terms

Glossary of Statistical Terms

NCI Dictionary of Genetics Terms

Terminology Resources
Quit Smoking Today
Search for
# A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All

teniposide
A semisynthetic derivative of podophyllotoxin with antineoplastic activity. Teniposide forms a ternary complex with the enzyme topoisomerase II and DNA, resulting in dose-dependent single- and double-stranded breaks in DNA, DNA: protein cross-links, inhibition of DNA strand religation, and cytotoxicity. This agent acts in the late S or early G phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

Synonyms:Thenvlidene-Lignan-P
Thenylidene-Lignan-P
VM26
US brand name:Vumon
Foreign brand name:Vehem
Abbreviations:EPT
PTG
Code name:VM-26
Chemical structure names:
  • [5R-[5Alpha,5a beta,8a alpha, 9beta(R*)]]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-(2-thienylmethylene)-beta-D-glucopyranosyl]oxy]furo[3',4':6,7]-naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
  • 4'-Demethylepipodophyllotoxin 9-(4,6-O-2-Thenylidene-beta-D-glucopyranoside)
  • 4'-Demethylepipodophyllotoxin-beta-D-thenylidine Glucoside



Previous:teloxantrone hydrochoride, Temodar, temozolomide, Tempostatin, temsirolimus
Next:tenofovir, terameprocol, terephthalamidine, teroxirone, Teslac

A Service of the National Cancer Institute
Department of Health and Human Services National Institutes of Health USA.gov