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cisplatin
An inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | CACP
cis-DDP
cis-diamminedichloro platinum (II)
cis-diamminedichloroplatinum
Cis-dichloroammine Platinum (II)
Cismaplat
Cisplatina
cis-platinous diamine dichloride
cis-platinum
cis-platinum II
cis-platinum II diamine dichloride
CPDD
Cysplatyna
DDP
PDD
Peyrone's Chloride
Peyrone's Salt
Platinoxan
platinum diamminodichloride | | | | US brand names: | | Platinol
Platinol-AQ | | | | Foreign brand names: | | Abiplatin
Blastolem
Briplatin
Cisplatyl
Citoplatino
Citosin
Lederplatin
Metaplatin
Neoplatin
Placis
Platamine
Platiblastin
Platiblastin-S
Platinex
Platinol- AQ
Platinol-AQ VHA Plus
Platiran
Platistin
Platosin | | | | Abbreviation: | | CDDP | | | | Chemical structure names: | | - (SP-4-2)-diamminedichloroplatinum
- platinum, diaminedichloro-, cis- (8CI)
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