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modafinil A synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090511155217im_/http://www.cancer.gov/images/spacer.gif) | Provigil | | ![](https://webarchive.library.unt.edu/eot2008/20090511155217im_/http://www.cancer.gov/images/spacer.gif) |
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