Seeing the Invisible by Solution NMR Spectroscopy |
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| Launch in standalone player | |
| Air date: | Wednesday, May 31, 2006, 3:00:00 PM |
| Category: | Wednesday Afternoon Lectures |
| Runtime: | 75 minutes |
| NLM Title: | Seeing the invisible by solution NMR spectroscopy [electronic resource] / Lewis E. Kay. |
| Series: | NIH director's Wednesday afternoon lecture series |
| Author: | Kay, Lewis E. National Institutes of Health (U.S.) |
| Publisher: | [Bethesda, Md. : National Institutes of Health, 2006] |
| Other Title(s): | NIH director's Wednesday afternoon lecture series |
| Abstract: | (CIT): Many biochemical processes proceed through the formation of functionally important intermediates. For example, ligand binding, enzyme catalysis and protein folding may all involve the formation of one or more intermediates along the reaction coordinate connecting the initial and final protein states. A complete understanding of each process requires, therefore, characterization of these intermediates in detail. While methods exist for studying the endpoints of these processes at atomic resolution in many cases, similar studies of the intermediates remain elusive. NMR methods for seeing such 'invisible' states will be described, along with a number of applications to protein folding illustrating the power of the methodology. |
| Subjects: | Nuclear Magnetic Resonance, Biomolecular |
| Publication Types: | Government Publications Lectures |
| Download: | Download
Video How to download a Videocast |
| NLM Classification: | QP 519.9.N83 |
| NLM ID: | 101285766 |
| CIT File ID: | 13263 |
| CIT Live ID: | 4292 |
| Permanent link: | http://videocast.nih.gov/launch.asp?13263 |