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NCI Drug Dictionary

anti-FLT-1 ribozyme
A nuclease-stabilized synthetic ribozyme with potential antineoplastic activity. Anti-Flt-1 ribozyme cleaves the mRNA encoding vascular endothelial growth factor 1 (VEGF-1, or Flt-1), thereby specifically inhibiting VEGF-stimulated angiogenesis, tumor growth, and metastasis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)

US brand name:Angiozyme
Foreign brand name:Angiozyme
Code name:RPI.4610

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