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anti-FLT-1 ribozyme A nuclease-stabilized synthetic ribozyme with potential antineoplastic activity. Anti-Flt-1 ribozyme cleaves the mRNA encoding vascular endothelial growth factor 1 (VEGF-1, or Flt-1), thereby specifically inhibiting VEGF-stimulated angiogenesis, tumor growth, and metastasis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif)
US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) | Angiozyme | | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) | Angiozyme | | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) | Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) | RPI.4610 | | ![](https://webarchive.library.unt.edu/eot2008/20090511154705im_/http://www.cancer.gov/images/spacer.gif) |
Previous: | anti-endoglin monoclonal antibody TRC105, anti-EpCAM antibody fragment -Pseudomonas exotoxin fusion protein, anti-EpCAM antibody fragment-bouganin fusion protein, anti-EpCAM/anti-CD3 recombinant bispecific monoclonal antibody MT110, anti-ErbB3 receptor monoclonal antibody MM-121 | Next: | anti-GP-3 monoclonal antibody, anti-HER3 monoclonal antibody U3-1287, anti-HGF monoclonal antibody SCH900105, anti-HIF-1alpha LNA antisense oligonucleotide EZN-2968, anti-human chorionic gonadotropin vaccine |
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