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fentanyl citrate pectin-based nasal spray A pectin-based, aqueous nasal spray containing the citrate salt of fentanyl, a synthetic lipophilic phenylpiperidine opioid, with analgesic activity. Fentanyl binds to and stimulates mu-opioid receptors in the central nervous system (CNS), mimicking the analgesic effect of endogenous opiates. Upon intranasal administration of this agent and contact with the nasal mucosa, pectin in low-viscosity aqueous solution gels in the presence of mucosal calcium ions; from this intranasal gel delivery platform, fentanyl is released into the systemic circulation in a relatively rapid but controlled and sustained manner. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509172007im_/http://www.cancer.gov/images/spacer.gif) | Nasalfent | | ![](https://webarchive.library.unt.edu/eot2008/20090509172007im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509172007im_/http://www.cancer.gov/images/spacer.gif) | Nasalfent | | ![](https://webarchive.library.unt.edu/eot2008/20090509172007im_/http://www.cancer.gov/images/spacer.gif) |
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