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clofibrate
An aryloxyisobutyric acid derivate with antihyperlipidemic activity. Although the exact mechanism of action has not been fully characterized, clofibrate may enhance the conversion of very-low-density lipoprotein (VLDL) to low-density lipoprotein (LDL), decreasing the production of hepatic VLDL, inhibiting cholesterol production, and increasing fecal excretion of neutral sterols. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Atromid-S | | | | Abbreviation: | | CFB | | | | Chemical structure names: | | - 2-(4-chlorophenoxy)-2-methylpropanoic acid ethyl ester
- ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
- ethyl p-chlorophenoxyisobyturate
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