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anaxirone A synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been shown to exhibit a broad spectrum of antineoplastic activity against experimental tumors, including those resistant to other alkylating agents. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) | triglycidylurazol | | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) | TGU | | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure name: | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) | 1,2,4-triglycidylurazol | | ![](https://webarchive.library.unt.edu/eot2008/20090509152303im_/http://www.cancer.gov/images/spacer.gif) |
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