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Malaria
 Understanding Malaria
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  Mosquito Research
  Malaria Vaccine Development Branch
  Biotech Approach to Malaria Vaccine Development


Malaria

Malaria Research in NIAID Labs

Laboratory of Malaria and Vector Research (LMVR)

About LMVR

LMVR is dedicated to studies of malaria and insect vectors of infectious diseases. Research groups in the laboratory maintain an array of on-campus and overseas activities investigating disease-transmitting insects and broad areas of malaria biology and pathogenesis. Basic discoveries from these investigations support searches for new drug treatments, diagnostic tools, and vaccines. 

Malaria Drug Resistance and Disease Severity

LMVR supports a spectrum of clinical and laboratory research projects on malaria and the mosquitoes responsible for its transmission.

Malaria Vaccine Development Branch (MVDB)

About MVDB

MVDB was commissioned in 2001 to research, develop, and produce prototype malaria vaccines and conduct early-phase clinical trials of promising vaccine candidates. Its overarching goal is to develop malaria vaccines that will reduce severe disease and death among African children and eliminate malaria from low-transmission areas of the world.

Scientists Pursue Vaccine Against Severe Malaria

MVDB is developing a vaccine that targets the “blood stage” of the deadliest malaria-causing parasite, Plasmodium falciparum. A blood-stage vaccine elicits immune responses capable of either destroying malaria parasites in the bloodstream or inhibiting parasites from infecting red blood cells.

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Graphic link to Life Cycle of the Malaria Parasite illustration. View an illustration about the life cycle of the malaria parasite.

See Also

  • Global Research, Africa
  • Vector Biology Research
  • Status of NIAID Adenovirus-based Vaccine Studies
  • Scientists seek genes responsible for drug resistance to aid development of better malaria drugs
  • New NIAID program focuses on interactions between immunology and the biology of the malaria parasite
  • Scientists pursue biotech approach to malaria vaccine development
  • Scientists search mosquito saliva for compounds that help transmit malaria
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    Graphic link to Life Cycle of the Malaria Parasite illustration. View an illustration about the life cycle of the malaria parasite.

    See Also

  • Global Research, Africa
  • Vector Biology Research
  • Status of NIAID Adenovirus-based Vaccine Studies
  • Scientists seek genes responsible for drug resistance to aid development of better malaria drugs
  • New NIAID program focuses on interactions between immunology and the biology of the malaria parasite
  • Scientists pursue biotech approach to malaria vaccine development
  • Scientists search mosquito saliva for compounds that help transmit malaria