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amonafide dihydrochloride
The dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | amonafide
amonafide hydrochloride
benzisoquinolinedione
nafidimide | | | | US brand name: | | Quinamed | | | | Abbreviations: | | AMON
BIDA | | | | Code name: | | M-FA-142 | | | | Chemical structure name: | | 1H-benz(de)isoquinoline-1,3(2H)-dione, 5-amino-2-(2-(dimethylamino)ethyl) | | |
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