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penicillamine
A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Depamine
D-mercaptovaline
D-Penicillamine | | | | US brand names: | | Cuprenil
Cuprimine
Depen
Perdolat
Sufortan | | | | Foreign brand names: | | Atamir
Cupripen
Distamine
Kelatin
Mercaptyl
Metalcaptase
Pendramine
Trolovol | | | | Chemical structure names: | | - 3-mercapto-D-valine
- alpha-amino-beta-methyl-beta-mercaptobutyric acid
- beta,beta-dimethylcysteine
- beta-thiovaline
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