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Pathology Tables for Peer Review
Pathology Tables for Peer Review
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NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 27 WEEK SSAC Facility: Battelle Columbus Laboratory Chemical CAS #: 93-15-2 Lock Date: 09/17/96 Cage Range: All Reasons For Removal: 25017 Scheduled Sacrifice Removal Date Range: 08/09/94 - 08/10/94 Treatment Groups: Include 002 0 MG/KG Include 010 300 MG/KG Include 001 0 MG/KG Include 009 300 MG/KG Note: Animals arranged according to days on test Page 1 NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 2| 3| 3| 3| 3| | A | 0 MG/KG | 8| 0| 0| 1| 3| | L | | 6| 0| 2| 3| 0| | | __________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Esophagus | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Colon | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Rectum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Cecum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Duodenum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Jejunum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Ileum | + + + + + | 5 | __________________________________________________________________________|____________| Liver | + + + + + | 5 | __________________________________________________________________________|____________| Pancreas | + + + + + | 5 | __________________________________________________________________________|____________| Salivary Glands | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Forestomach | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Glandular | + + + + + | 5 | _____________________________________________________________________________________________________________________| | CARDIOVASCULAR SYSTEM | | | | | | __________________________________________________________________________|____________| Blood Vessel | + + + + + | 5 | __________________________________________________________________________|____________| Heart | + + + + + | 5 | _____________________________________________________________________________________________________________________| | ENDOCRINE SYSTEM | | | | | | __________________________________________________________________________|____________| Adrenal Cortex | + + + + + | 5 | __________________________________________________________________________|____________| Adrenal Medulla | + + + + + | 5 | __________________________________________________________________________|____________| Islets, Pancreatic | + + + + + | 5 | __________________________________________________________________________|____________| Parathyroid Gland | + M + + + | 4 | __________________________________________________________________________|____________| Pituitary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Thyroid Gland | + + + + + | 5 | _____________________________________________________________________________________________________________________| | GENERAL BODY SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | GENITAL SYSTEM | | | | | | __________________________________________________________________________|____________| Clitoral Gland | + + + + + | 5 | __________________________________________________________________________|____________| Ovary | + + + + + | 5 | __________________________________________________________________________|____________| Uterus | + + + + + | 5 | _____________________________________________________________________________________________________________________| | HEMATOPOIETIC SYSTEM | | | | | | __________________________________________________________________________|____________| Bone Marrow | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node | + | 1 | __________________________________________________________________________|____________| Lymph Node, Mandibular | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mesenteric | + + + + + | 5 | __________________________________________________________________________|____________| Spleen | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 2| 3| 3| 3| 3| | A | 0 MG/KG | 8| 0| 0| 1| 3| | L | | 6| 0| 2| 3| 0| | | __________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM - cont | | | | | | __________________________________________________________________________|____________| Thymus | + + + + + | 5 | _____________________________________________________________________________________________________________________| | INTEGUMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Mammary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Skin | + + + + + | 5 | _____________________________________________________________________________________________________________________| | MUSCULOSKELETAL SYSTEM | | | | | | __________________________________________________________________________|____________| Bone | + + + + + | 5 | _____________________________________________________________________________________________________________________| | NERVOUS SYSTEM | | | | | | __________________________________________________________________________|____________| Brain | + + + + + | 5 | _____________________________________________________________________________________________________________________| | RESPIRATORY SYSTEM | | | | | | __________________________________________________________________________|____________| Lung | + + + + + | 5 | __________________________________________________________________________|____________| Nose | + + + + + | 5 | __________________________________________________________________________|____________| Trachea | + + + + + | 5 | _____________________________________________________________________________________________________________________| | SPECIAL SENSES SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | URINARY SYSTEM | | | | | | __________________________________________________________________________|____________| Kidney | + + + + + | 5 | __________________________________________________________________________|____________| Urinary Bladder | + + + + + | 5 | __________________________________________________________________________________________________________________________________ SYSTEMIC LESIONS | | | __________________________________________________________________________|____________| Multiple Organs | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 4| 4| 4| 5| 5| | A | 300 | 8| 8| 8| 0| 3| | L | MG/KG | 1| 3| 4| 5| 8| | | __________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Esophagus | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Colon | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Rectum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Cecum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Duodenum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Jejunum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Ileum | + + + + + | 5 | __________________________________________________________________________|____________| Liver | + + + + + | 5 | __________________________________________________________________________|____________| Pancreas | + + + + + | 5 | __________________________________________________________________________|____________| Salivary Glands | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Forestomach | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Glandular | + + + + + | 5 | _____________________________________________________________________________________________________________________| | CARDIOVASCULAR SYSTEM | | | | | | __________________________________________________________________________|____________| Blood Vessel | + + + + + | 5 | __________________________________________________________________________|____________| Heart | + + + + + | 5 | _____________________________________________________________________________________________________________________| | ENDOCRINE SYSTEM | | | | | | __________________________________________________________________________|____________| Adrenal Cortex | + + + + + | 5 | __________________________________________________________________________|____________| Adrenal Medulla | + + + + + | 5 | __________________________________________________________________________|____________| Islets, Pancreatic | + + + + + | 5 | __________________________________________________________________________|____________| Parathyroid Gland | + M M + + | 3 | __________________________________________________________________________|____________| Pituitary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Thyroid Gland | + + + + + | 5 | _____________________________________________________________________________________________________________________| | GENERAL BODY SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | GENITAL SYSTEM | | | | | | __________________________________________________________________________|____________| Clitoral Gland | + + + + + | 5 | __________________________________________________________________________|____________| Ovary | + + + + + | 5 | __________________________________________________________________________|____________| Uterus | + + + + + | 5 | _____________________________________________________________________________________________________________________| | HEMATOPOIETIC SYSTEM | | | | | | __________________________________________________________________________|____________| Bone Marrow | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mandibular | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mesenteric | + + + + + | 5 | __________________________________________________________________________|____________| Spleen | + + + + + | 5 | __________________________________________________________________________|____________| Thymus | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS FEMALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 4| 4| 4| 5| 5| | A | 300 | 8| 8| 8| 0| 3| | L | MG/KG | 1| 3| 4| 5| 8| | | __________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM - cont | | | | | | _____________________________________________________________________________________________________________________| | INTEGUMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Mammary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Skin | + + + + + | 5 | _____________________________________________________________________________________________________________________| | MUSCULOSKELETAL SYSTEM | | | | | | __________________________________________________________________________|____________| Bone | + + + + + | 5 | _____________________________________________________________________________________________________________________| | NERVOUS SYSTEM | | | | | | __________________________________________________________________________|____________| Brain | + + + + + | 5 | _____________________________________________________________________________________________________________________| | RESPIRATORY SYSTEM | | | | | | __________________________________________________________________________|____________| Lung | + + + + + | 5 | __________________________________________________________________________|____________| Nose | + + + + + | 5 | __________________________________________________________________________|____________| Trachea | + + + + + | 5 | _____________________________________________________________________________________________________________________| | SPECIAL SENSES SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | URINARY SYSTEM | | | | | | __________________________________________________________________________|____________| Kidney | + + + + + | 5 | __________________________________________________________________________|____________| Urinary Bladder | + + + + + | 5 | __________________________________________________________________________________________________________________________________ SYSTEMIC LESIONS | | | __________________________________________________________________________|____________| Multiple Organs | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 0| 0| 0| 0| 0| | A | 0 MG/KG | 3| 3| 3| 3| 5| | L | | 3| 5| 7| 8| 8| | | __________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Esophagus | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Colon | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Rectum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Cecum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Duodenum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Jejunum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Ileum | + + + + + | 5 | __________________________________________________________________________|____________| Liver | + + + + + | 5 | __________________________________________________________________________|____________| Pancreas | + + + + + | 5 | __________________________________________________________________________|____________| Salivary Glands | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Forestomach | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Glandular | + + + + + | 5 | _____________________________________________________________________________________________________________________| | CARDIOVASCULAR SYSTEM | | | | | | __________________________________________________________________________|____________| Blood Vessel | + + + + + | 5 | __________________________________________________________________________|____________| Heart | + + + + + | 5 | _____________________________________________________________________________________________________________________| | ENDOCRINE SYSTEM | | | | | | __________________________________________________________________________|____________| Adrenal Cortex | + + + + + | 5 | __________________________________________________________________________|____________| Adrenal Medulla | + + + + + | 5 | __________________________________________________________________________|____________| Islets, Pancreatic | + + + + + | 5 | __________________________________________________________________________|____________| Parathyroid Gland | + + + + + | 5 | __________________________________________________________________________|____________| Pituitary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Thyroid Gland | + + + + + | 5 | _____________________________________________________________________________________________________________________| | GENERAL BODY SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | GENITAL SYSTEM | | | | | | __________________________________________________________________________|____________| Epididymis | + + + + + | 5 | __________________________________________________________________________|____________| Preputial Gland | + + + + + | 5 | __________________________________________________________________________|____________| Prostate | + + + + + | 5 | __________________________________________________________________________|____________| Seminal Vesicle | + + + + + | 5 | __________________________________________________________________________|____________| Testes | + + + + + | 5 | _____________________________________________________________________________________________________________________| | HEMATOPOIETIC SYSTEM | | | | | | __________________________________________________________________________|____________| Bone Marrow | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mandibular | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mesenteric | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 0| 0| 0| 0| 0| | A | 0 MG/KG | 3| 3| 3| 3| 5| | L | | 3| 5| 7| 8| 8| | | __________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM - cont | | | | | | __________________________________________________________________________|____________| Spleen | + + + + + | 5 | __________________________________________________________________________|____________| Thymus | + + + + + | 5 | _____________________________________________________________________________________________________________________| | INTEGUMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Mammary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Skin | + + + + + | 5 | _____________________________________________________________________________________________________________________| | MUSCULOSKELETAL SYSTEM | | | | | | __________________________________________________________________________|____________| Bone | + + + + + | 5 | _____________________________________________________________________________________________________________________| | NERVOUS SYSTEM | | | | | | __________________________________________________________________________|____________| Brain | + + + + + | 5 | _____________________________________________________________________________________________________________________| | RESPIRATORY SYSTEM | | | | | | __________________________________________________________________________|____________| Lung | + + + + + | 5 | __________________________________________________________________________|____________| Nose | + + + + + | 5 | __________________________________________________________________________|____________| Trachea | + + + + + | 5 | _____________________________________________________________________________________________________________________| | SPECIAL SENSES SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | URINARY SYSTEM | | | | | | __________________________________________________________________________|____________| Kidney | + + + + + | 5 | __________________________________________________________________________|____________| Urinary Bladder | + + + + + | 5 | __________________________________________________________________________________________________________________________________ SYSTEMIC LESIONS | | | __________________________________________________________________________|____________| Multiple Organs | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 2| 2| 2| 2| 2| | A | 300 | 1| 2| 4| 6| 6| | L | MG/KG | 2| 9| 3| 4| 8| | | __________________________________________________________________________________________________________________________________ ALIMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Esophagus | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Colon | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Rectum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Large, Cecum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Duodenum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Jejunum | + + + + + | 5 | __________________________________________________________________________|____________| Intestine Small, Ileum | + + + + + | 5 | __________________________________________________________________________|____________| Liver | + + + + + | 5 | __________________________________________________________________________|____________| Pancreas | + + + + + | 5 | __________________________________________________________________________|____________| Salivary Glands | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Forestomach | + + + + + | 5 | __________________________________________________________________________|____________| Stomach, Glandular | + + + + + | 5 | _____________________________________________________________________________________________________________________| | CARDIOVASCULAR SYSTEM | | | | | | __________________________________________________________________________|____________| Blood Vessel | + + + + + | 5 | __________________________________________________________________________|____________| Heart | + + + + + | 5 | _____________________________________________________________________________________________________________________| | ENDOCRINE SYSTEM | | | | | | __________________________________________________________________________|____________| Adrenal Cortex | + + + + + | 5 | __________________________________________________________________________|____________| Adrenal Medulla | + + + + + | 5 | __________________________________________________________________________|____________| Islets, Pancreatic | + + + + + | 5 | __________________________________________________________________________|____________| Parathyroid Gland | + + + + + | 5 | __________________________________________________________________________|____________| Pituitary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Thyroid Gland | + + + + + | 5 | _____________________________________________________________________________________________________________________| | GENERAL BODY SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | GENITAL SYSTEM | | | | | | __________________________________________________________________________|____________| Epididymis | + + + + + | 5 | __________________________________________________________________________|____________| Preputial Gland | + + + + + | 5 | __________________________________________________________________________|____________| Prostate | + + + + + | 5 | __________________________________________________________________________|____________| Seminal Vesicle | + + + + + | 5 | __________________________________________________________________________|____________| Testes | + + + + + | 5 | _____________________________________________________________________________________________________________________| | HEMATOPOIETIC SYSTEM | | | | | | __________________________________________________________________________|____________| Bone Marrow | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mandibular | + + + + + | 5 | __________________________________________________________________________|____________| Lymph Node, Mesenteric | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically NTP Experiment-Test: 05187-09 NEOPLASMS BY INDIVIDUAL ANIMAL (SYSTEMIC LESIONS ABRIDGED) Report: PEIRPT17 Study Type: CHRONIC METHYLEUGENOL Date: 07/20/98 Route: GAVAGE Time: 08:46:24 __________________________________________________________________________________________________________________________________ | 1| 1| 1| 1| 1| | | DAY ON TEST | 8| 8| 8| 8| 8| | | | 4| 4| 4| 4| 4| | | _____________________________________________________________________________________________________________________| T (*) | | 0| 0| 0| 0| 0| | O | FISCHER 344 RATS MALE | 0| 0| 0| 0| 0| | T | ANIMAL ID | 2| 2| 2| 2| 2| | A | 300 | 1| 2| 4| 6| 6| | L | MG/KG | 2| 9| 3| 4| 8| | | __________________________________________________________________________________________________________________________________ HEMATOPOIETIC SYSTEM - cont | | | | | | __________________________________________________________________________|____________| Spleen | + + + + + | 5 | __________________________________________________________________________|____________| Thymus | + + + + + | 5 | _____________________________________________________________________________________________________________________| | INTEGUMENTARY SYSTEM | | | | | | __________________________________________________________________________|____________| Mammary Gland | + + + + + | 5 | __________________________________________________________________________|____________| Skin | + + + + + | 5 | _____________________________________________________________________________________________________________________| | MUSCULOSKELETAL SYSTEM | | | | | | __________________________________________________________________________|____________| Bone | + + + + + | 5 | _____________________________________________________________________________________________________________________| | NERVOUS SYSTEM | | | | | | __________________________________________________________________________|____________| Brain | + + + + + | 5 | _____________________________________________________________________________________________________________________| | RESPIRATORY SYSTEM | | | | | | __________________________________________________________________________|____________| Lung | + + + + + | 5 | __________________________________________________________________________|____________| Nose | + + + + + | 5 | __________________________________________________________________________|____________| Trachea | + + + + + | 5 | _____________________________________________________________________________________________________________________| | SPECIAL SENSES SYSTEM | | | | | | None | | | _____________________________________________________________________________________________________________________| | URINARY SYSTEM | | | | | | __________________________________________________________________________|____________| Kidney | + + + + + | 5 | __________________________________________________________________________|____________| Urinary Bladder | + + + + + | 5 | __________________________________________________________________________________________________________________________________ SYSTEMIC LESIONS | | | __________________________________________________________________________|____________| Multiple Organs | + + + + + | 5 | __________________________________________________________________________________________________________________________________ * : Total animals with tissue examined microscopically; total animals with tumor + : Tissue examined microscopically M : Missing tissue X : Lesion present A : Autolysis precludes evaluation I : Insufficient tissue BLANK : Not examined microscopically ------------------------------------------------------------ ---------- END OF REPORT ---------- ------------------------------------------------------------
Web page last updated on November 15, 2004
The National Institute of Environmental Health Sciences is one of the National Institutes of Health within the U.S. Department of Health and Human Services. The National Toxicology Program is headquartered on the NIEHS campus in Research Triangle Park, NC.