Pathology Tables for Peer Review
The National Toxicology Program
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Columbus TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153) DATE: 06/05/03
EXPERIMENT: 96021 TEST: 01 TIME: 10:27:20
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: GAVAGE NTP: C96021
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE COLUMBUS TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153) DATE: 06/05/03
EXPERIMENT: 96021 TEST: 01 TIME: 10:38:35
SPECIES: RATS, SPRAGUE-DAWLEY
TEST TYPE: TWO YEAR ROUTE: ORAL GAVAGE NTP: C96021
CONT: NO1-ES-75411 CAS: 35065-27-1
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR ORAL GAVAGE STUDY OF TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153)
==========================================================================================================================
WEEK 0 UG/KG 10 UG/KG 100 UG/KG 300 UG/KG 1000 UG/KG
---------------- ---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
==================================================================================================================================
B 172.6 98 174.4 101.0 86 173.6 100.6 98 173.2 100.3 98 170.6 98.8 98
1 172.6 98 174.4 101.0 86 173.6 100.6 98 173.2 100.3 98 170.6 98.8 98
2 192.8 98 196.1 101.7 86 193.7 100.5 98 197.1 102.2 98 194.9 101.1 98
3 212.1 98 213.6 100.7 86 212.4 100.1 98 217.3 102.5 98 216.4 102.0 98
4 229.4 98 233.3 101.7 86 230.9 100.7 98 233.5 101.8 98 234.1 102.0 98
5 238.4 98 242.2 101.6 86 239.9 100.6 98 243.7 102.2 98 242.2 101.6 98
6 249.0 98 252.2 101.3 86 249.5 100.2 98 252.2 101.3 98 252.1 101.2 98
7 251.8 98 257.8 102.4 86 256.5 101.9 98 259.5 103.1 98 259.9 103.2 98
8 258.1 98 265.2 102.8 86 263.7 102.2 98 266.2 103.1 98 266.0 103.1 98
9 265.0 98 270.5 102.1 86 267.4 100.9 98 268.0 101.1 98 269.6 101.7 98
10 270.1 98 275.0 101.8 86 268.9 99.6 98 275.5 102.0 97 273.0 101.1 98
11 271.7 98 278.3 102.4 86 270.9 99.7 98 278.7 102.6 97 278.0 102.3 98
12 274.5 98 281.6 102.6 86 277.7 101.2 98 281.0 102.4 97 284.0 103.5 98
13 280.2 98 287.5 102.6 86 283.5 101.2 98 287.4 102.6 97 287.1 102.5 98
17 288.6 82 (I) 292.6 101.4 76 (I) 292.3 101.3 82 (I) 294.5 102.0 81 (I) 292.2 101.2 82 (I)
21 298.0 82 302.2 101.4 76 298.6 100.2 82 303.3 101.8 81 302.5 101.5 82
25 301.9 82 307.6 101.9 76 306.9 101.7 82 310.2 102.7 81 309.4 102.5 82
29 307.5 82 311.8 101.4 76 310.4 100.9 82 313.9 102.1 81 314.2 102.2 82
33 312.5 65 (I) 320.5 102.6 66 (I) 318.0 101.8 66 (I) 322.3 103.1 64 (I) 321.1 102.8 66 (I)
37 319.8 65 327.1 102.3 64 322.7 100.9 66 328.7 102.8 64 327.8 102.5 66
40 318.9 65 327.3 102.6 62 323.9 101.6 66 329.5 103.3 62 329.3 103.3 66
45 328.3 65 334.6 101.9 62 331.5 101.0 66 338.8 103.2 62 336.4 102.5 66
49 333.5 65 336.1 100.8 59 337.1 101.1 66 344.7 103.4 61 342.9 102.8 66
53 340.7 57 (I) 338.2 99.3 48 (I) 339.0 99.5 58 (I) 344.2 101.0 52 (I) 342.7 100.6 56 (I)
57 348.2 52 347.1 99.7 43 344.7 99.0 53 347.8 99.9 47 350.8 100.7 50
61 353.0 49 354.4 100.4 42 354.1 100.3 52 354.6 100.5 47 356.6 101.0 50
65 360.9 47 360.6 99.9 41 355.3 98.4 49 363.2 100.6 46 367.5 101.8 50
69 366.4 47 370.5 101.1 41 361.1 98.6 49 366.0 99.9 44 368.3 100.5 48
73 371.6 46 374.9 100.9 37 369.7 99.5 47 376.0 101.2 43 369.7 99.5 45
77 376.9 45 376.8 100.0 33 369.0 97.9 40 374.3 99.3 39 374.5 99.4 42
81 377.5 41 381.8 101.1 31 377.5 100.0 39 378.8 100.3 37 382.3 101.3 40
85 384.1 40 386.0 100.5 31 382.5 99.6 39 385.6 100.4 36 386.1 100.5 39
89 387.7 34 393.3 101.4 27 383.9 99.0 38 391.2 100.9 34 392.2 101.2 36
92 387.0 32 401.5 103.7 22 386.4 99.8 37 387.3 100.1 32 393.5 101.7 31
97 394.5 28 379.8 96.3 20 395.0 100.1 36 400.3 101.5 29 377.4 95.7 28
101 387.7 24 385.6 99.5 16 403.6 104.1 28 379.7 97.9 23 366.4 94.5 25
TERM. SAC. 24 16 28 21 20
==========================================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR ORAL GAVAGE STUDY OF TOXIC EQUIVALENCY FACTOR EVALUATION (PCB 153)
========================================================
3000 UG/KG 3000 UG/KG STOP
WEEK ---------------- ----------------
AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=======================================================
B 173.9 100.8 80 170.3 98.7 50
1 173.9 100.8 80 170.3 98.7 50
2 198.4 102.9 80 187.9 97.5 50
3 218.7 103.1 80 213.2 100.5 50
4 233.8 101.9 80 233.1 101.6 50
5 242.6 101.8 80 238.7 100.1 50
6 253.6 101.8 80 253.9 102.0 50
7 260.8 103.6 80 260.7 103.5 50
8 267.4 103.6 80 267.8 103.8 50
9 271.5 102.5 80 270.4 102.0 50
10 275.8 102.1 80 272.0 100.7 50
11 278.0 102.3 80 273.5 100.7 50
12 282.0 102.7 80 283.0 103.1 50
13 287.9 102.7 79 287.0 102.4 50
17 295.9 102.5 69 (I) 292.6 101.4 50
21 304.2 102.1 69 301.1 101.0 50
25 311.0 103.0 69 310.5 102.8 50
29 313.9 102.1 69 314.0 102.1 48
33 317.6 101.6 59 (I) 317.7 101.7 48
37 324.8 101.6 59 324.1 101.3 47
40 324.1 101.6 59 324.3 101.7 47
45 327.5 99.8 59 333.6 101.6 47
49 332.0 99.6 59 340.5 102.1 47
53 335.7 98.5 49 (I) 343.9 100.9 46
57 338.2 97.1 46 350.0 100.5 46
61 345.2 97.8 46 354.1 100.3 45
65 344.1 95.3 42 361.1 100.1 44
69 350.3 95.6 41 363.8 99.3 42
73 348.8 93.9 37 370.8 99.8 42
77 349.6 92.8 34 370.6 98.3 40
81 354.4 93.9 32 383.3 101.5 40
85 363.5 94.6 30 391.5 101.9 39
89 358.4 92.4 27 390.6 100.7 35
92 350.9 90.7 25 396.4 102.4 31
97 351.4 89.1 23 407.3 103.2 26
101 359.5 92.7 22 398.9 102.9 23
TERM. SAC. 21 20
========================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
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