National Toxicology Program

CASRN: 140-56-7

Formula: C8 H11 N3 O3 S.NA

Synonyms/Common Names:

• (4-)DIMETHYLAMINO)PHENYL)-DIAZENESULFONIC ACID SODIUM SALT (9CI)

Known Uses:

FUNGICIDAL TREATMENT OF SEEDS, SUGARCANE AND LAWNS

Short-Term Toxicity

• 14-Day (Dosed-Feed)  (C03010) Completed 
  • NTIS No. PB287443  (Peer Review 04/26/1978)
    Citation: Bioassay of Formulated Fenaminosulf for Possible Carcinogenicity (CAS No. 140-56-7)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Dosed-Feed)  (C03010) Completed 
  • NTIS No. PB287443  (Peer Review 04/26/1978)
    Citation: Bioassay of Formulated Fenaminosulf for Possible Carcinogenicity (CAS No. 140-56-7)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: 0,.008,.060 %/10 PER GROUP

Long-Term Carcinogenicity

• 2-Year (Dosed-Feed)  (C03010) Report Complete 
  • TR-101 (NTIS No. PB287443)  (Peer Review 04/26/1978)
    Bioassay of Formulated Fenaminosulf for Possible Carcinogenicity (CAS No. 140-56-7)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Negative 
  • Female Rats Negative 
  • Male Mice Negative 
  • Female Mice Negative 
  • Dose: R&FM: 0,.05,.10 (AVG), MM: 0,.10,.19 (AVG) %/50 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (386052) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Positive 
• Mouse Lymphoma  (321970) Completed 
  •  Positive 
• Salmonella  (136878) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Positive