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lidocaine patch 5% A transdermal patch containing a 5 percent aqueous base solution of the synthetic amide-type anesthetic lidocaine with analgesic activity. Upon topical application and transdermal delivery, the active ingredient lidocaine binds to and blocks voltage-gated sodium channels in the neuronal cell membrane; lidocaine-mediated stabilization of neuronal membranes inhibits the initiation and conduction of nerve impulses and produces a reversible local anesthesia. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509211835im_/http://www.cancer.gov/images/spacer.gif) | Lidoderm | | ![](https://webarchive.library.unt.edu/eot2008/20090509211835im_/http://www.cancer.gov/images/spacer.gif) |
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