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tributyrin
A triglyceride prodrug of butyric acid with potential antineoplastic activity. Butyrate, the active metabolite of tributyrin, inhibits histone deacetylase, resulting in increased differentiation, decreased proliferation, cell cycle arrest, and apoptosis in some tumor cell lines. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | butyryl triglyceride
glyceryl tributyrate | | | | Abbreviation: | | TB | | | | Chemical structure names: | | - 1,2,3-propanetriyl butanoate
- 1,2,3-tributyrylglycerol
- butanoic acid 1,2,3-propanetriyl ester
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