Definition of menogaril - National Cancer Institute Drug Dictionary

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menogaril
A semisynthetic derivative of the anthracycline antineoplastic antibiotic nogalamycin. Menogaril intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin. Check for or using this agent. ()

US brand name:		Menogarol

Abbreviations:		7-OMEN MEN TUT-7

Code name:		U-52047

Chemical structure names:		[2R-(2alpha,3beta,4alpha,5beta,6alpha,11alpha,13alpha)]-4-(dimethylamino)-3,4,5,6,11,12,13,14-octahydro-3,5,8,10,13-pentahydroxy-11-methoxy-6,13-dimethyl-2,6-epoxy-2H-naphthaceno[1,2-b]oxocin-9,16-dione 7-(R)-O-methylnogarol 7-con-O-methylnogarol 7-con-O-methylnorgarol

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