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monoclonal antibody HuHMFG1 A humanized monoclonal antibody directed against MUC1, a mucin glycoprotein overexpressed in breast and other carcinomas. Monoclonal antibody HuHMFG1 stimulates antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing MUC1, resulting in a decrease in tumor burden. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | humanized human milk fat globule-1 monoclonal antibody humanized IgG1 monoclonal antibody HMFG-1 | | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | Therex | | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | HuHMFG1 MOAB HuHMFG1 | | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | Code names: | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) | AS1402 R1550 | | ![](https://webarchive.library.unt.edu/eot2008/20090509161733im_/http://www.cancer.gov/images/spacer.gif) |
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