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U.S. National Institutes of Health National Cancer Institute

SEER Stat Fact Sheets


Cancer:  

Note: Mortality data for the current data year is not yet available (view details).

The following information is based on NCI’s SEER Cancer Statistics Review1.

Incidence

SEER Incidence

From 2002-2006, the median age at diagnosis for cancer of the kidney and renal pelvis was 64 years of age2. Approximately 1.3% were diagnosed under age 20; 1.5% between 20 and 34; 6.1% between 35 and 44; 16.4% between 45 and 54; 24.6% between 55 and 64; 24.3% between 65 and 74; 20.0% between 75 and 84; and 5.7% 85+ years of age.

The age-adjusted incidence rate was 13.6 per 100,000 men and women per year. These rates are based on cases diagnosed in 2002-2006 from 17 SEER geographic areas.

Incidence Rates by Race
Race/EthnicityMaleFemale
All Races18.6 per 100,000 men9.5 per 100,000 women
White19.2 per 100,000 men9.9 per 100,000 women
Black21.3 per 100,000 men10.3 per 100,000 women
Asian/Pacific Islander 9.6 per 100,000 men4.8 per 100,000 women
American Indian/Alaska Native a21.7 per 100,000 men14.1 per 100,000 women
Hispanic b17.6 per 100,000 men9.6 per 100,000 women

Trends in Rates

Trends in rates can be described in many ways. Information for trends over a fixed period of time, for example 1996-2006, can be evaluated by the annual percentage change (APC) (See Fast Stats for trends over fixed time intervals) . If there is a negative sign before the number, the trend is a decrease; otherwise it is an increase. If there is an asterisk after the APC then the trend was significant, that is, one believes that it is beyond chance, i.e. 95% sure, that the increase or decrease is real over the period 1996-2006. If the trend is not significant, the trend is usually reported as stable or level. Joinpoint analyses can be used over a long period of time to evaluate when changes in the trend have occurred along with the APC which shows how much the trend has changed between each of the joinpoints.

The joinpoint trend in SEER cancer incidence with associated APC(%) for cancer of the kidney and renal pelvis between 1975-2006
All Races
Male and FemaleMaleFemale
TrendPeriodTrendPeriodTrendPeriod
2.0*1975-20061.7*1975-20062.3*1975-2006

Survival & Stage

Survival rates can be calculated by different methods for different purposes. The survival rates presented here are based on the relative survival rate, which measures the survival of the cancer patients in comparison to the general population to estimate the effect of cancer. The overall 5-year relative survival rate for 1999-2005 from 17 SEER geographic areas was 68.4%. Five-year relative survival rates by race and sex were: 68.1% for white men; 69.1% for white women; 64.7% for black men; 67.4% for black women.

The stage distribution based on Summary Stage 2000 shows that 58% of kidney and renal pelvis cancer cases are diagnosed while the cancer is still confined to the primary site (localized stage); 18% are diagnosed after the cancer has spread to regional lymph nodes or directly beyond the primary site; 19% are diagnosed after the cancer has already metastasized (distant stage) and for the remaining 4% the staging information was unknown. The corresponding 5-year relative survival rates were: 90.4% for localized; 62.3% for regional; 10.4% for distant; and 37.5% for unstaged. (See Fast Stats for more detailed statistics)

Prevalence

On January 1, 2006, in the United States there were approximately 266,068 men and women alive who had a history of cancer of the kidney and renal pelvis -- 156,166 men and 109,902 women. This includes any person alive on January 1, 2006 who had been diagnosed with cancer of the kidney and renal pelvis at any point prior to January 1, 2006 and includes persons with active disease and those who are cured of their disease. Prevalence can also be expressed as a percentage and it can also be calculated for a specific amount of time prior to January 1, 2006 such as diagnosed within 5 years of January 1, 2006. (See Fast Stats for more detailed statistics, and Overview of Prevalence Statistics for methodology)


References

All statistics in this report are based on SEER incidence statistics. Most can be found within:

Horner MJ, Ries LAG, Krapcho M, Neyman N, Aminou R, Howlader N, Altekruse SF, Feuer EJ, Huang L, Mariotto A, Miller BA, Lewis DR, Eisner MP, Stinchcomb DG, Edwards BK (eds). SEER Cancer Statistics Review, 1975-2006, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2006/, based on November 2008 SEER data submission, posted to the SEER web site, 2009.

Footnotes

1 Kidney and Renal Pelvis Section (http://seer.cancer.gov/csr/ 1975_2006/results_merged/ sect_11_kidney_pelvis.pdf)
2 Table I-11 (http://seer.cancer.gov/csr/1975_2006/results_single/sect_01_table.11_2pgs.pdf)
* The APC is significantly different from zero (p<.05).
a Incidence data for Hispanics is based on NHIA and excludes cases from Alaska Native Registry. Hispanic death rates exclude deaths from Minnesota, New Hampshire and North Dakota.
b Incidence and mortality data for American Indians/Alaska Natives is based on the CHSDA (Contract Health Service Delivery Area) counties.

Definitions

Annual percent change (APC)
The average annual percent change over several years. The APC is used to measure trends or the change in rates over time. For information on how this is calculated, go to Trend Algortihms in the SEER*Stat Help system. The calculation involves fitting a straight line to the natural logarithm of the data when it is displayed by calendar year.

Joinpoint analyses
A statistical model for characterizing cancer trends which uses statistical criteria to determine how many times and when the trends in incidence or mortality rates have changed. The results of joinpoint are given as calendar year ranges, and the annual percent change (APC) in the rates over each period.

Survival rates
Survival examines how long after diagnosis people live. Cancer survival is measured in a number of different ways depending on the intended purpose.

Relative survival rate
A measure of net survival that is calculated by comparing observed (overall) survival with expected survival from a comparable set of people that do not have cancer to measure the excess mortality that is associated with a cancer diagnosis.

Stage distribution
Stage provides a measure of disease progression, detailing the degree to which the cancer has advanced. Two methods commonly used to determine stage are AJCC and SEER Summary Stage. The AJCC method (see Collaborative Staging Method) is more commonly used in the clinical settings, while SEER has strived to provide consistent definitions over time with their Local/Regional/Distant staging.

Lifetime risk
The probability of developing cancer in the course of one's lifespan. Lifetime risk may also be discussed in terms of the probability of developing or of dying from cancer. Based on cancer rates from 2004 to 2006, it was estimated that men had about a 44 percent chance of developing cancer in their lifetimes, while women had about a 37 percent chance.

Probability of developing cancer
The chance that a person will develop cancer in his/her lifetime.

Prevalence
The number of people who have received a diagnosis of cancer during a defined time period, and who are alive on the last day of that period. Most prevalence data in SEER is for limited duration because information on cases diagnosed before 1973 is not generally available.