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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Andrea Bucceri
Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.
BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE, Current Contents, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Cancer 2009, 9 :128
Zebrafish embryos allow the analysis of tumor cells' circulation, migration and micrometastasis formation in real-time and constitute a simple and sensitive in vivo model for the study of tumor invasion and metastatic behavior.
BMC Cancer 2009, 9 :106
Fluorescence and ultrasound imaging of orthotopic pancreatic tumors in mouse models are potentially a useful combined modality for monitoring tumor growth in real time and thereby enhance the utility of these models for pre-clinical drug testing.
BMC Cancer 2009, 9 :88
In colorectal cancer patients, circulating levels of cell death markers cytokeratin 18 (CK18) and its caspase-degradation product CK18-Asp396 are predictive of tumor progression and prognosis and may be useful for treatment selection and patient monitoring.
BMC Cancer 2009, 9 :80
Distinction between invasive ductal carcinoma and invasive lobular carcinoma may be possible by assessing the silenced status of the ADAM33 gene by means of promotor hypermethylation, thereby improving the diagnosis and treatment of these cancer types.
BMC Cancer 2009, 9 :78
The IL1RN polymorphism in the interleukin-1 gene may be a useful prognostic tool for breast cancer as carriage of two mutant alleles is independently associated with reduced survival in Caucasian patients.
New York, USA. 10 November 2007 BMC Proceedings 2008,
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Research article
The 271 G>A polymorphism of kinase insert domain-containing receptor gene regulates its transcription level in patients with non-small cell lung cancer She-Juan An, Zhi-Hong Chen, Qiu-Xiong Lin, Jian Su, Hua-Jun Chen, Jia-Ying Lin, Yi-Long Wu BMC Cancer 2009, 9 :144 (12 [Abstract ] [Provisional PDF ]
Research article
Expression of Hyaluronan Synthases (HAS1-3) and Hyaluronidases (HYAL1-2) in Serous Ovarian Carcinomas: Inverse Correlation between HYAL1 and Hyaluronan Content Timo K Nykopp, Kirsi Rilla, Reijo Sironen, Markku I Tammi, Raija H Tammi, Kirsi Hamalainen, Anna-Mari Heikkinen, Marja Komulainen, Veli-Matti Kosma, Maarit Anttila BMC Cancer 2009, 9 :143 (12 [Abstract ] [Provisional PDF ]
Research article
MP470, a novel receptor tyrosine kinase inhibitor, in combination with Erlotinib inhibits the HER family/PI3K/Akt pathway and tumor growth in prostate cancer Wenqing Qi, Larry Cooke, Amy Stejskal, Christopher J Riley, Kimiko Della Croce, Jose W Saldanha, David Bearss, Daruka Mahadevan BMC Cancer 2009, 9 :142 (11 [Abstract ] [Provisional PDF ]
Research article
Ethnicity and incidence of Hodgkin lymphoma in Canadian population Punam Pahwa, Chandima P Karunanayake, John J Spinelli, James A Dosman, Helen H McDuffie BMC Cancer 2009, 9 :141 (11 [Abstract ] [Provisional PDF ]
Research article
Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer: a case-control study Karin Broberg, Elizabeth Huynh, Karin Schlawicke Engstrom, Jonas Bjork, Maria Albin, Christian Ingvar, Hakan Olsson, Mattias Hoglund BMC Cancer 2009, 9 :140 (11 [Abstract ] [Provisional PDF ]
Research article
Does the Availability of Positron Emission Tomography modify Diagnostic Strategies for Solitary Pulmonary Nodules?
An Observational Study in France Irawati Lemonnier, Cedric Baumann, Nicolas Jay, Kazem Alzahouri, Patrick Arveux, Damien Jolly, Catherine Lejeune, Michel Velten, Fabien Vitry, Marie-Christine Woronoff-Lemsi, Francis Guillemin BMC Cancer 2009, 9 :139 (11 [Abstract ] [Provisional PDF ]
Research article
ALA-D activity is a reliable marker for oxidative stress in bone marrow transplantation patients Thissiane L Goncalves, Dalila M Benvegnu, Gabriela Bonfanti, Andressa V Frediani, Joao Batista T Rocha BMC Cancer 2009, 9 :138 (8 [Abstract ] [Provisional PDF ]
Research article
A case-control study on the combined effects of p53 and p73 polymorphisms on head and neck cancer risk in an Italian population Paola Galli, Gabriella Cadoni, Mariangela Volante, Emma De Feo, Rosarita Amore, Arianna Giorgio, Dario Arzani, Gaetano Paludetti, Gualtiero Ricciardi, Stefania Boccia BMC Cancer 2009, 9 :137 (8 [Abstract ] [Provisional PDF ]
Research article
Collagen mRNA levels changes during colorectal cancer carcinogenesis Hanne Skovbjerg, Dorit Anthonsen, Inger MB Lothe, Kjell M Tveit, Elin H Kure, Lotte K Vogel BMC Cancer 2009, 9 :136 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library Ming-Szu Hung, Zhidong Xu, Yu-Ching Lin, Jian-Hua Mao, Cheng-Ta Yang, Pey-Jium Chang, David M Jablons, Liang You BMC Cancer 2009, 9 :135 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
TCF/beta-catenin plays an important role in HCCR-1 oncogene expression Gwang-won Cho, Mi Kim, Seung Kim, Seon Ha, Hyun Kim, Sanghee Kim, Jin W Kim BMC Molecular Biology 2009, 10 :42 (12 [Abstract ] [Provisional PDF ]
Research
Estimating the incidence of lung cancer attributable to occupational exposure in Iran Alireza Mosavi-Jarrahi, Mohammadali Mohagheghi, Bita Kalaghchi, Yasaman Mousavi-Jarrahi, Mohammad Kazem Noori Population Health Metrics 2009, 7 :7 (12 [Abstract ] [Provisional PDF ]
Research
HA117 gene increased the multidrug resistance of K562 cells in vitro: an investigation to the function of a novel gene related to drug resistance Yuxia Guo, Gaihuan Zheng, Xianqing Jin, Youhua Xu, Xiaomei Liu, Qing Luo, Zhenzhen Zhao, Yong Chen Journal of Experimental & Clinical Cancer Research 2009, 28 :63 (12 [Abstract ] [Provisional PDF ]
Research
Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract George Miller, Nicholas D Socci, Deepti Dhall, Michael D'Angelica, Ronald P DeMatteo, Peter J Allen, Bhuvanesh Singh, Yuman Fong, Leslie H Blumgart, David S Klimstra, William R Jarnagin Journal of Experimental & Clinical Cancer Research 2009, 28 :62 (12 [Abstract ] [Provisional PDF ]
Review
Dermoscopy as a technique for the early identification of foot melanoma Ivan R Bristow, Jonathan Bowling Journal of Foot and Ankle Research 2009, 2 :14 (12 [Abstract ] [Provisional PDF ]
Letter
Co-incidental increase in gene copy number of ERBB2 and LRIG1 in breast cancer Ingrid Ljuslinder, Irina Golovleva, Roger Henriksson, Kjell Grankvist, Beatrice Malmer, H Breast Cancer Research 2009, 11 :403 (12 [PDF ]
Primary research
Nucleic acid distribution pattern as a possible biomarker for metabolic activities of neoplastic cells: a digitally-aided fluorescence microscopy study on normal and neoplastic lymphocytes of acute and chronic canine lymphocytic leukemia Godwin N. Isitor, Mervyn Campbell, Shivananda B. Nayak Cancer Cell International 2009, 9 :13 (11 [Abstract ] [Provisional PDF ]
Research
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion. Satish B Cheepala, Weihong Yin, Zanobia Syed, Jennifer N Gill, Alaina McMillian, Heather E Kleiner, Mark Lynch, Raja Loganantharaj, Marjan Trutschl, Urska Cvek, John L Clifford Molecular Cancer 2009, 8 :27 (11 [Abstract ] [Provisional PDF ]
Case report
Cutaneous skull metastasis from uterine leiomyosarcoma: a case report Nikolaos Barbetakis, Dimitrios Paliouras, Christos Asteriou, Georgios Samanidis, Athanassios Kleontas, Doxakis Anestakis, Kostas Kaplanis, Christodoulos Tsilikas World Journal of Surgical Oncology 2009, 7 :45 (11 [Abstract ] [Provisional PDF ]
Research article
Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line Aslaug Aamodt Muggerud, Henrik Edgren, Maija Wolf, Kristine Kleivi, Emelyne Dejeux, Jorg Tost, Therese Sorlie, Olli Kallioniemi BMC Medical Genomics 2009, 2 :26 (11 [Abstract ] [Provisional PDF ]
Featured articles 
kan Hedman