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Tuberculosis
 Understanding TB
  Overview
  What is TB?
  TB in History
  Cause
  Transmission
  Symptoms
  Diagnosis
  Treatment
  Prevention
  TB and HIV
  Publications
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Tuberculosis (TB)

Overview

In developed countries, such as the United States, many people think tuberculosis (TB) is a disease of the past. TB, however, is still a leading killer of young adults worldwide. Some 2 billion people—one-third of the world's population—are thought to be infected with TB bacteria, Mycobacterium tuberculosis (Mtb).

TB is a chronic bacterial infection. It is spread through the air and usually infects the lungs, although other organs and parts of the body can be involved as well. Most people who are infected with Mtb harbor the bacterium without symptoms (have latent TB), but some will develop active TB disease. According to World Health Organization (WHO) estimates, each year, 8 million people worldwide develop active TB and nearly 2 million die.

One in 10 people who are infected with Mtb may develop active TB at some time in their lives. The risk of developing active disease is greatest in the first year after infection, but active disease often does not occur until many years later.

TB in the United States

In 2006, the Centers for Disease Control and Prevention (CDC) reported 13,799 cases of active TB. While the overall rate of new TB cases continues to decline in the United States since national reporting began in 1953, the annual decrease in TB cases has slowed from an average of 7.1 percent (1993–2000) to the current average of 3.8 percent (2001–2005), according to CDC. In addition to those with active TB, an estimated 10 to 15 million people in the United States have latent TB.

Minorities are affected disproportionately by TB, which occurs among foreign-born individuals nearly nine times as frequently as among people born in the United States. This is partially because they were often exposed to Mtb in their country of origin before moving to the United States. In 2004, a very high percentage of Asians (95 percent) and Hispanics (75 percent) who were born outside the United States were reported to have TB.

Related Links

Government

Centers for Disease Control and Prevention

Non-government

World Health Organization

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Volunteer for Clinical Studies
Volunteer for NIAID-funded clinical studies related to tuberculosis on ClinicalTrials.gov.

See Also

Global Research, Africa

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Volunteer for Clinical Studies
Volunteer for NIAID-funded clinical studies related to tuberculosis on ClinicalTrials.gov.

See Also

Global Research, Africa