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The National Reye's Syndrome Foundation
PO Box 829 - Bryan - OH 43506
1-800-233-7393
nrsf@reyessyndrome.org
Reye's Syndrome Awareness Month is September - our Ribbon Color is Process Blue.
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Click here to learn how important it is to talk about Reye's with your Teens and Young Adults. Learn why it is not just Aspirin Products, but all Salicylate containing products.
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Reye's Syndrome, a deadly disease, strikes swiftly and can attack any child, teen, or adult without warning. All body organs are affected, with the liver and brain suffering most seriously.

While the cause and cure remain unknown, research has established a link between Reye's Syndrome and the use of aspirin and other salicylate containing medications, over the counter products, and topical use products.

In 1974, the National Reye's Syndrome Foundation was incorporated, becoming the first citizen group to generate a concerted, organized lay movement to eradicate Reye's Syndrome.

Save A Life; Learn about Reye's Syndrome

National Reye's Syndrome Foundation Presents;

Reye's Syndrome: A Real and Present Danger

Please click the play button to start the Video


We would like to thank DCTV 5, Defiance Ohio for their assistance with this media conversion.

What Is Reye's Syndrome?

Reye's Syndrome is a disease which affects all organs of the body, but most lethally the liver and the brain. Reye's Syndrome is a two-phase illness because it is almost always associated with a previous viral infection, such as influenza, cold, or chicken pox. Scientists do know that Reye's Syndrome is not contagious and the cause is unknown. Reye's Syndrome is often misdiagnosed as encephalitis, meningitis, diabetes, drug overdose, poisoning, Sudden Infant Death Syndrome, or psychiatric illness.

Reye's Syndrome tends to appear with greatest frequency during January, February, and March when influenza is most common. Cases are reported in every month of the year. An epidemic of flu or chicken pox is commonly followed by an increase in the number of cases of Reye's Syndrome.

When Reye's Syndrome develops, it typically occurs when a person is beginning to recover from a viral illness. Abnormal accumulations of fat begin to develop in the liver and other organs of the body, along with a severe increase of pressure in the brain. Unless diagnosed and treated successfully, death is common, often within a few days. A person's life depends upon early diagnosis. Statistics indicate an excellent chance of recovery when Reye's Syndrome is diagnosed and treated in its earliest stages. The later the diagnosis and treatment, the more severely reduced are chances for successful recovery and survival.

Stages of Reye's Syndrome:

  • Stage I:
    Persistent or continuous vomiting
    Signs of brain dysfunction:
    Listlessness
    Loss of pep and energy
    Drowsiness
  • Stage II:
    Personality changes:
    Irritability
    Aggressive behavior
    Disorientation:
    Confusion
    Irrational behavior
    Combative
    Delirium, convulsions, coma

Reye's Syndrome should be suspected in a person if this pattern of symptoms appear during, or most commonly, after a viral illness. Not all of the symptoms have to occur, nor do they have to be displayed in this order. Fever is not usually present. Many diseases have symptoms in common. Physicians and medical staff in emergency rooms who have not had experience in treating Reye's Syndrome may misdiagnose the disease. (See Emergency Room Information) The symptoms of Reye's Syndrome in infants do not follow a typical pattern. For example, vomiting may be replaced with diarrhea, and they may display irregular breathing.


The Foundation's Top Objectives are:

... AWARENESS - to aid in early detection and educate the public and medical communities about the risk involved with using aspirin and other salicylates.

... SERVICE - to provide emotional support and guidance to families experiencing the trauma of Reye's Syndrome.

... RESEARCH - to support investigation into the disease's cause, management, treatment and prevention, as well as study its impact on survivors.


If this site has proved helpful to you, a donation from you would assist us in keeping this site up-to-date. To make a tax deductible donation to the National Reye's Syndrome Foundation, click here.

To become a member of the National Reye's Syndrome Foundation, click here.

Know that your donations and memberships allow us to continue spreading Awareness about Reye's Syndrome to new mom's, new medical professionals, caregivers, schools, daycare centers, churches, and immigrants, and to a global population who can now access this website. You make a difference, a life and death difference. -- Thank You.

Report A Case of Reye's Syndrome

Tylenol and Ibuprophen do not contain Salicylates and can be used as a fever reducer.
When taking any medication we recommend you check with your doctor first.

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