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PROMIS: The First Four YearsUse SHIFT+ENTER to open the menu (new window).

The Patient Reported Outcomes Measurement Information System (PROMIS):

A Walk Through the First Four Years

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FDA on PROMISUse SHIFT+ENTER to open the menu (new window).
"FDA joins NIH in the goal of ensuring that PROMIS results in meaningful measurement of the impact of medical product treatment." 
Laurie Burke, MPH, RPh
Director, Study Endpoint and Label Development
Center for Drug Evaluation and research
U.S. Food and Drug Administration


Assessment Center Training WorkshopsUse SHIFT+ENTER to open the menu (new window).
July 17, 2009 (Chicago, IL)
New E-mail Contact for Assessment CenterUse SHIFT+ENTER to open the menu (new window).

Welcome to PROMIS

In late 2004, a group of outcomes scientists from seven institutions and the National Institutes of Health (NIH) formed a cooperative network funded under the NIH Roadmap for Medical Research Initiative to re-engineer the clinical research enterprise.


This initiative -the Patient-Reported Outcomes Measurement Information System (PROMIS) - aims to revolutionize the way patient-reported outcome tools are selected and employed in clinical research and practice evaluation. It will also establish a national resource for accurate and efficient measurement of patient-reported symptoms and other health outcomes in clinical practice. As part of the NIH Roadmap, NIH funded six primary research sites and a statistical coordinating center as the PROMIS network. PROMIS aims to develop ways to measure patient-reported symptoms, such as pain and fatigue, and aspects of health-related quality of life across a wide variety of chronic diseases and conditions. "There is a pressing need to better quantify clinically important symptoms and outcomes that are now difficult to measure," says NIH Director Elias A. Zerhouni, MD. "Our clinical research communities would benefit greatly from efficient, consistent, well-validated approaches to measuring these and other subjective outcomes."Clinical outcome measures, such as x-rays and lab tests, have minimally immediate relevance to the day-to-day functioning of patients with chronic diseases such as arthritis, multiple sclerosis, and asthma, as well as chronic pain conditions. Often, the best way patients can judge the effectiveness of treatments is by perceived changes in symptoms. One main goal of the PROMIS initiative is to develop a set of publicly available computerized adaptive tests for the clinical research community.

The NIH Roadmap is a series of far-reaching initiatives designed to transform the Nation's medical research capabilities and speed the movement of research discoveries from the bench to the bedside. It provides a framework of the priorities NIH must address to optimize its entire research portfolio, and it lays out a vision for a more efficient and productive system of medical research. For more information about the NIH Roadmap, please visit the Web site at http://www.nihroadmap.nih.gov.


Assessment Center Links

  Assessment Center User Manual
  Assessment Center Workshop, July 17th in Chicago
  Lodging and transportation for July 17th workshop
  Introduction to PROMIS, Item Response Theory, Computerized Adaptive Testing, and Assessment Center Slide Presentation (Richard Gershon)

Whats New

  PROMIS: A Walk Through the First Four years
  Demonstration CAT
  Assessment Center Release 3. Click here to see description of release 3 features
  Summary of PROMIS Wave 2 Protocols

What's Coming Soon...

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  Research Team Login
  Assessment Center
  PROMIS Mid-Course Review Report
  NIH Roadmap for Medical Research link to 'Re-engineering the Clinical Research Enterprise'
  Demonstration CAT
  Neuro-QOL:Quality of Life in Neurological Disorders
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